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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
52 Results for "
quinoline-based hydrazones
" in MedChemExpress (MCE) Product Catalog:
Products (52)
52 Results for "quinoline-based hydrazones" in MCE Product Catalog:
5
5 Cited Publications
Cat. No.: HY-16261B
CAS No.: 480998-12-7
Synonyms: (E/Z)-Aldoxorubicin hydrochloride; Doxorubicin(6-maleimidocaproyl)hydrazone hydrochloride
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MC-DOXHZN ((E/Z)-Aldoxorubicin; Doxorubicin(6-maleimidocaproyl)hydrazone) hydrochloride is an albumin-binding proagent of Doxorubicin (HY-15142A) (DNA topoisomerase II inhibitor), with acid-sensitive properties. MC-DOXHZN hydrochloride can be used to synthesize ADC .
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Pyridoxal isonicotinoyl hydrazone is an orally active and lipophilic iron-specific chelator that acts as a non-competitive inhibitor of ferrochelatase (FECH) by binding iron ions. Pyridoxal isonicotinoyl hydrazone disrupts heme biosynthesis, leading to reduced FECH stability and increased protoporphyrin IX (PPIX) accumulation. Pyridoxal isonicotinoyl hydrazone is promising for research of iron-overload diseases (e.g., β-thalassemia) .
4
4 Cited Publications
Synonyms: CX05168; CX04328
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LEDGIN6 (CX05168) is a quinoline-based protein-protein interaction inhibitor of LEDGF/p75 and HIV integrase .
3
FAPI-46 is a quinoline-based fibroblast activation protein (FAP)-targeted tracer. Use radioactivity FAPI-46 labeled with 68Ga or 177Lu can be used for tumor imaging in a variety of cancers and has higher tumor uptake rates and longer tumor accumulation .
1
1 Cited Publications
Cat. No.: HY-W077680
CAS No.: 1126-58-5
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Girard's P reagent is a reagent used in organic chemistry. Girard's P reagent is used to react with vanillin to form a hydrazone derivative, which is then combined with an ion selective electrode (ISE) to develop a potentiometric method for the determination of vanillin. Girard's P reagent can be used in the development of ion selective electrodes and in the study of organic analysis .
Cat. No.: HY-15932
CAS No.: 82692-93-1
Synonyms: TOOS sodium salt
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Cat. No.: HY-W074541
CAS No.: 123-46-6
Synonyms: Trimethylacetohydrazideammonium chloride
Cat. No.: HY-16261A
CAS No.: 151038-96-9
Synonyms: (E/Z)-Aldoxorubicin; Doxorubicin(6-maleimidocaproyl)hydrazone
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Research Areas:
MC-DOXHZN ((E/Z)-Aldoxorubicin; Doxorubicin(6-maleimidocaproyl)hydrazone) is an albumin-binding proagent of Doxorubicin (HY-15142A) (DNA topoisomerase II inhibitor), with acid-sensitive properties. MC-DOXHZN can be used to synthesize ADC .
Cat. No.: HY-161752
CAS No.: 16371-55-4
Antibacterial agent 224 is a potent and selective synthetic hydrazone inhibitor against the Salmonella PhoP/PhoQ system .
Cat. No.: HY-136131
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NH2-PEG4-hydrazone-DBCO is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . NH2-PEG4-hydrazone-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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Sivifene (A-007) is a triaryl hydrazone. Sivifene has anticancer activity and immunomodulatory effects. Sivifene regulates immune regulation by upregulating CD45 T lymphocyte surface receptors .
Cat. No.: HY-W009411
CAS No.: 33008-06-9
Cat. No.: HY-W012617
CAS No.: 553-53-7
Synonyms: Nicotinic acid hydrazide
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Nicotinohydrazide (Nicotinic acid hydrazide) is a precursor used for synthesizing hydrazone derivatives with antibacterial and antifungal activities. Nicotinohydrazide can be used in studies of bacterial and fungal infections .
Cat. No.: HY-W013677
CAS No.: 456-22-4
Cat. No.: HY-155908
CAS No.: 474922-26-4
Synonyms: DSPE-PEG10000-NH2 ammonium
DSPE-PEG10000-Amine ammonium (DSPE-PEG10000-NH2 ammonium) is a PEGylated distearoylphosphatidylethanolamine lipid with a terminal primary amino group. DSPE-PEG10000-Amine ammonium serves as a liposome component, and its surface bears reactive primary amino groups that enable covalent conjugation via the formation of bis-aryl hydrazone bonds .
FAPI-2 is a quinoline-based fibroblast activation protein (FAP)-targeting ligand that can be labeled as 68Ga-FAPI-2 and used as a PET tracer for cancer diagnosis. FAPI-2 has advantages such as fast tracer kinetics, no need for fasting preparation, and being unaffected by blood glucose .
Cat. No.: HY-136079
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Methyltetrazine-PEG4-hydrazone-DBCO is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-PEG4-hydrazone-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Methyltetrazine-PEG4-hydrazone-DBCO also contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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Cyanoacetohydrazide is a pharmaceutical intermediate. Cyanoacetohydrazide can be used to synthesize acylhydrazide hydrazone derivatives with antibacterial or anti-tumor activity .
Cat. No.: HY-19221
CAS No.: 133012-05-2
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Bay-y-1015 is an orally active quinoline-based 5-lipoxygenase inhibitor. Bay-y-1015 inhibits LTB4 and LTC4 synthesis. Bay-y-1015 can be used in the research of inflammatory diseases .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
