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210

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4

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34

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9

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16

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16

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0351
    Taurine
    Maximum Cited Publications
    17 Publications Verification

    2-Aminoethanesulfonic acid

    		 Autophagy Endogenous Metabolite Metabolic Disease Cancer
    Taurine, a sulphur-containing amino acid and an organic osmolyte involved in cell volume regulation, provides a substrate for the formation of bile salts, and plays a role in the modulation of intracellular free calcium concentration. Taurine has the ability to activate autophagy in adipocytes .
    Taurine
  • HY-112624
    Dextran
    2 Publications Verification

    Dextran 40

    		 Bacterial Cardiovascular Disease Cancer
    Dextran (Dextran 40) has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander.
    Dextran
  • HY-B0264
    Guaifenesin

    Guaiacol glyceryl ether; Guaiphenesin; Glycerol guaiacolate

    		 Mucin Neurological Disease Inflammation/Immunology
    Guaifenesin (Guaiacol glyceryl ether), a constituent of guaiac resin from the wood of Guajacum officinale Linné, is an expectorant. Guaifenesin can alleviate cough discomfortby increasing sputum volume and decreasing its viscosity, thereby promoting effective cough .
    Guaifenesin
  • HY-12807
    FIPI
    5 Publications Verification

    5-Fluoro-2-indolyl deschlorohalopemide

    		 Phospholipase Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
    FIPI is a phospholipase D (PLD) inhibitor with an IC50 for PLD1 and PLD2 of about 25 nM. FIPI regulates cytoskeletal recombination, cell diffusion and chemotaxis. FIPI can be used in cancer research. In addition, FIPI can enhance the secretion and aggregation of platelet dense particles, inhibit thrombosis, reduce ischemic stroke infarct volume and improve nerve function .
    FIPI
  • HY-112624C
    Dextran (MW 40000)

    		Biochemical Assay Reagents Endogenous Metabolite Others
    Dextran (MW 40000) is a complex carbohydrate polymer consisting of glucose molecules linked by glycosidic bonds. Dextran has excellent solubility in water, making it useful as a viscosity modifier or stabilizer in foods, paints and adhesives. In the biomedical field, dextran is often used as a plasma expander because of its ability to increase blood volume when administered intravenously. It can also be modified to create dextran-based drug delivery systems, such as targeted nanoparticles.
    Dextran (MW 40000)
  • HY-110135
    NBI-31772
    3 Publications Verification

    		 IGF-1R Neurological Disease Inflammation/Immunology
    NBI-31772 is a non-selective IGFBP inhibitor (Ki=47 nM). NBI-31772 has neuroprotective effects and reduces infarct volume during cerebral ischemia. NBI-31772 can also restore or enhance proteoglycan synthesis in osteoarticular chondrocytes. In addition, NBI-31772 also increases the effect of IGF3 on zebrafish oocyte maturation .
    NBI-31772
  • HY-P99370
    Landogrozumab
    1 Publications Verification

    LY2495655; Anti-GDF8 / Myostatin Reference Antibody (landogrozumab)

    		 TGF-beta/Smad Inflammation/Immunology Cancer
    Landogrozumab (LY2495655) is an humanized anti-myostatin monoclonal antibody. Landogrozumab effectively improves muscle volume, hand grip strength and function. Landogrozumab can be used for the research of muscle wasting disease .
    Landogrozumab
  • HY-B0351S
    Taurine-d4
    1 Publications Verification

    2-Aminoethanesulfonic acid-d4

    		 Autophagy Endogenous Metabolite Metabolic Disease
    Taurine-d4 is the deuterium labeled Taurine. Taurine, a sulphur-containing amino acid and an organic osmolyte involved in cell volume regulation, provides a substrate for the formation of bile salts, and plays a role in the modulation of intracellular free calcium concentration. Taurine has the ability to activate autophagy in adipocytes .
    Taurine-d4
  • HY-P10275
    Tat-NTS peptide

    		Apoptosis Neurological Disease
    Tat-NTS peptide is a cell-penetrating peptide with neuroprotective effects. Tat-NTS peptide can specifically inhibit the nuclear translocation of ANXA1 and reduce neuronal apoptosis in ischemic areas. Moreover, Tat-NTS peptide can reduce the volume of cerebral ischemic infarction and can be used in the research of ischemic stroke .
    Tat-NTS peptide
  • HY-P0133
    (Arg) 9

    Nona-L-arginine; Peptide R9

    		 Ser/Thr Protease Neurological Disease
    (Arg)9 (Nona-L-arginine) is a cell-penetrating peptide (CPP) made up of 9 arginine residues, which is an inhibitor of serine endoprotease Furin. (Arg)9 has neuroprotective property, exhibits neuroprotective activity with an IC50 of 0.78 μM in the glutamic acid model .
    (Arg) 9
  • HY-112624F
    CY7-Dextran (MW 4000)

    		Fluorescent Dye Others
    CY7-Dextran (MW 4000) is a fluorescent dye that consists of CY7 (HY-D0825) and Dextran (HY-112624) (Ex=740 nm; Em=770 nm). CY7-Dextran (MW 4000) can be used as a cell volume indicator and delineates the thin peripheral edges of the cells .
    CY7-Dextran (MW 4000)
  • HY-P0133A
    (Arg)9 TFA
    1 Publications Verification

    Nona-L-arginine TFA; Peptide R9 TFA

    		 Ser/Thr Protease Neurological Disease
    (Arg)9 (Nona-L-arginine) TFA is a cell-penetrating peptide (CPP) made up of 9 arginine residues. (Arg)9 TFA has neuroprotective property, exhibits neuroprotective activity with an IC50 of 0.78 μM in the glutamic acid model .
    (Arg)9 TFA
  • HY-118470
    Butaxamine hydrochloride

    Butoxamin hydrochloride

    		 Adrenergic Receptor Endocrinology
    Butaxamine (Butoxamin) hydrochloride is a specific β2-adrenergic receptor blocker. Butaxamine hydrochloride inhibits the decreases in urine volume in ethanol-anesthetized, water-diuretic rats .
    Butaxamine hydrochloride
  • HY-B0235
    Trichlormethiazide
    2 Publications Verification

    		 Carbonic Anhydrase Metabolic Disease
    Trichlormethiazide is an orally active thiazide diuretic, with antihypertensive effect. Trichlormethiazide increases urine volume (UV), Na and K excretion and tends to improve the depressed creatinine clearance (CCRE) in acute renal failure rats model .
    Trichlormethiazide
  • HY-160888
    ASP8302

    		mAChR Endocrinology
    ASP8302 is a positive and allosteric muscarinic M3 receptor modulator. ASP8302 improves voiding efficiency and reduced residual urine volume in two voiding dysfunction models. ASP8302 can be used for research of underactive bladder .
    ASP8302
  • HY-DY1002
    H2DCFDA (solution)

    		Reactive Oxygen Species (ROS) Fluorescent Dye Others
    H2DCFDA (DCFH-DA) (solution) is a cell-permeable probe used to detect intracellular reactive oxygen species (ROS) (Ex/Em=488/525 nm) .
    Solvent and concentration: DMSO: 10 mM.
    The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
    H2DCFDA (solution)
  • HY-B0351S2
    Taurine-13C2,15N

    2-Aminoethanesulfonic acid-13C2,15N

    		 Isotope-Labeled Compounds Autophagy Endogenous Metabolite Metabolic Disease
    Taurine- 13C2, 15N is the 13C- and 15N- labeled Taurine. Taurine, a sulphur-containing amino acid and an organic osmolyte involved in cell volume regulation, provides a substrate for the formation of bile salts, and plays a role in the modulation of intracellular free calcium concentration. Taurine has the ability to activate autophagy in adipocytes .
    Taurine-13C2,15N
  • HY-DY1049
    Thioflavin T (solution)

    		Amyloid-β Others
    Thioflavin T (solution) is a cationic Benzothiazole dye that shows enhanced fluorescence upon binding to amyloid in tissue sections. Excitation max.: ~385 nm (free) ; ~450 nm (bound) ; Emission max.: ~445 nm (free) ; ~485 nm (bound) .
    Solvent and Concentration: Sterile water: 10 mM
    The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
    Thioflavin T (solution)
  • HY-D2709
    Cy3 Dextran (MW 20000)

    		Fluorescent Dye Others
    Cy3 Dextran (MW 20000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
    Cy3 Dextran (MW 20000)
  • HY-P0133B
    (Arg)9 acetate
    1 Publications Verification

    Nona-L-arginine acetate; Peptide R9 acetate

    		 Ser/Thr Protease Neurological Disease
    (Arg)9 (Nona-L-arginine) acetate is a cell-penetrating peptide (CPP) made up of 9 arginine residues. (Arg)9 acetate has neuroprotective property, exhibits neuroprotective activity with an IC50 of 0.78 μM in the glutamic acid model .
    (Arg)9 acetate
  • HY-B0351R
    Taurine (Standard)
    1 Publications Verification

    2-Aminoethanesulfonic acid (Standard)

    		 Reference Standards Autophagy Endogenous Metabolite Metabolic Disease Cancer
    Taurine (Standard) is the analytical standard of Taurine. This product is intended for research and analytical applications. Taurine, a sulphur-containing amino acid and an organic osmolyte involved in cell volume regulation, provides a substrate for the formation of bile salts, and plays a role in the modulation of intracellular free calcium concentration. Taurine has the ability to activate autophagy in adipocytes .
    Taurine (Standard)
  • HY-B0351S1
    Taurine-13C2

    2-Aminoethanesulfonic acid-13C2

    		 Autophagy Endogenous Metabolite Metabolic Disease
    Taurine- 13C2 is the 13C-labeled Taurine. Taurine, a sulphur-containing amino acid and an organic osmolyte involved in cell volume regulation, provides a substrate for the formation of bile salts, and plays a role in the modulation of intracellular free calcium concentration. Taurine has the ability to activate autophagy in adipocytes .
    Taurine-13C2
  • HY-101960A
    Tyrphostin A51

    AG-183

    		 EGFR Cancer
    Tyrphostin A51 is a potent protein tyrosine kinase (PTK) inhibitor. Tyrphostin A51 inhibits the volume-dependent release of [ 3H]taurine in a dose-dependent manner. Tyrphostin A51 markedly reduces cellular tyrosyl phosphorylation level. Tyrphostin A51 inhibits both basal and EGF-induced human bone cell proliferation .
    Tyrphostin A51
  • HY-D2708
    Cy3 Dextran (MW 10000)

    		Fluorescent Dye Others
    Cy3 Dextran (MW 10000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
    Cy3 Dextran (MW 10000)
  • HY-W250145
    Acid Black 2

    Nigrosine

    		 Biochemical Assay Reagents Others
    Acid Black 2 (Nigrosine) is an alcohol-soluble absorber used to mimic skin pigmentation in tissue-mimicking phantoms. Acid Black 2 acts as an absorber in silicone-based thin tissue phantoms to simulate varying melanosome volume fractions in skin .
    Acid Black 2
  • HY-132280
    Tirilazad

    U 74006F free base

    		 Reactive Oxygen Species (ROS) SARS-CoV Virus Protease Neurological Disease Inflammation/Immunology
    Tirilazad (U 74006F free base) is a neuroprotective agent. Tirilazad can also bind tightly to the main protease of the COVID-19 virus and exert anti-SARS-CoV-2 activity. Tirilazad scavenges hydroxyl and lipid peroxyl free radicals and maintains the levels of endogenous antioxidants. Tirilazad reduces cerebral infarct volume and improves neurobehavioral scores in animal models of focal ischemia. Tirilazad can be used in research related to ischemic stroke and subarachnoid hemorrhage .
    Tirilazad
  • HY-W248583
    Pyrromethene 650

    PM650

    		 Fluorescent Dye Others
    Pyrromethene 650 (PM650) is a green-fluorescent polar tracer dye. It is used for investigations of membrane fusion, lysis, and gap-junctional communication and to detect volume changes in cells or liposomes.
    Pyrromethene 650
  • HY-169779
    PTX80

    		p62 Cancer
    PTX80 is an antagonist of p62 with an IC50 value of 31.18 nM. PTX80 reduces tumor volume in an HCT116 colorectal cancer mouse xenograft model .
    PTX80
  • HY-N2412
    Irisolidone
    1 Publications Verification

    		 Chloride Channel Neurological Disease Cancer
    Irisolidone is a major isoflavone found in Pueraria lobata flowers. Irisolidone exhibits potent hepatoprotective activity. Irisolidone shows the high efficacy for volume-regulated anion channels (VRAC) blockade (IC50=9.8 μM) .
    Irisolidone
  • HY-126193
    JS-K

    		NO Synthase Apoptosis Autophagy Reactive Oxygen Species (ROS) Cancer
    JS-K is a NO donor that reacts with glutathione to generate NO at physiological pH. JS-K induces reactive oxygen species (ROS) to mediate apoptosis. JS-K induces autophagy. JS-K inhibits invasion. JS-K has a broad spectrum anti-proliferative activity in cancer cells. JS-K reduces tumor volume and causes necrosis of implanted tumors in mice .
    JS-K
  • HY-DY1070
    AQC (solution)

    		Fluorescent Dye Others
    AQC (6-Aminoquinolyl-N-hydroxysccinimidyl carbamate) (solution) is a reagent used for amino acid or protein sequence analysis by HPLC with fluorescence detection. AQC reacts with primary and secondary amino acids to yield fluorescent derivates, allowing amino acid detection at under-picomolar levels .
    Solvent and concentration: DMSO: 10 mM
    The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
    AQC (solution)
  • HY-D2466
    Cy3 Dextran (MW 70000)

    		Fluorescent Dye Cardiovascular Disease
    Cy3 Dextran (MW 70000) is a fluorescent labeling reagent that conjugates the Cy3 (HY-D0822) fluorescent dye with Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. The maximum emission wavelength of Cy3 is approximately 562-570 nm. Dextran inhibits platelet aggregation and coagulation factors, and serves as a plasma volume expander .
    Cy3 Dextran (MW 70000)
  • HY-172241
    Tapencarium

    RZL-012; Utenpanium chloride

    		 Ser/Thr Kinase Metabolic Disease
    Tapencarium (RZL-012) is a serine/threonine kinase inhibitor. Tapencarium can reduce subcutaneous fat volume. Tapencarium is promising for research of fat-related disorders such as Dercum’s disease and aesthetic applications .
    Tapencarium
  • HY-D1777
    Pyrromethene 605

    PM605

    		 Fluorescent Dye Others
    Pyrromethene 605 (PM605) is a green-fluorescent polar tracer dye. It is used for investigations of membrane fusion, lysis, and gap-junctional communication and to detect volume changes in cells or liposomes.
    Pyrromethene 605
  • HY-P3501
    Fexapotide

    NX-1207

    		 Apoptosis Cancer
    Fexapotide (NX-1207) induces apoptosis selectively, reducing prostate volume at a cellular level. Fexapotide can be used in lower urinary tract symptoms (LUTS) and benign prostatic hyperplasia (BPH) research .
    Fexapotide
  • HY-B0264R
    Guaifenesin (Standard)

    Guaiacol glyceryl ether(Standard); Guaiphenesin(Standard); Glycerol guaiacolate (Standard)

    		 Reference Standards Others Neurological Disease Inflammation/Immunology
    Guaifenesin (Standard) is the analytical standard of Guaifenesin. This product is intended for research and analytical applications. Guaifenesin (Guaiacol glyceryl ether), a constituent of guaiac resin from the wood of Guajacum officinale Linné, is an expectorant. Guaifenesin can alleviate cough discomfortby increasing sputum volume and decreasing its viscosity, thereby promoting effective cough .
    Guaifenesin (Standard)
  • HY-DY1056
    Texas Red (solution)

    		Fluorescent Dye Neurological Disease
    Texas Red (Sulforhodamine 101) (solution) is an amphoteric rhodamine red fluorescent dye (excitation/emission: 586/605 nm). Texas Red is used extensively for investigating neuronal morphology and acts as acell type-selective fluorescent marker of astrocytes bothin vivoand in slice preparations .
    Solvent and concentration: DMSO: 10 mM
    The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
    Texas Red (solution)
  • HY-124304
    Pinokalant

    LOE-908

    		 TRP Channel SARS-CoV Neurological Disease
    Pinokalant is a broad-spectrum and non-selectivecation channel inhibitor. Pinokalant significantly reduces cortical infarct volume. Pinokalant o improves the metabolic and electrophysiologic status of the ischemic penumbra. Pinokalant reduces lesion size on magnetic resonance images in the acute phase following middle cerebral artery occlusion in rats. Pinokalant has the potential for the research of stroke. Pinokalant also shows anti-SARS-CoV-2 activity .
    Pinokalant
  • HY-W581820
    Iron(II) succinate

    Ferrous succinate

    		 Biochemical Assay Reagents Cardiovascular Disease
    Iron(II) succinate (Ferrous succinate) is an orally active and organic acid iron supplement (ferrous salt). Iron(II) succinate improves hematological parameters in iron-deficiency anemia rats, including hemoglobin, red blood cells, hematocrit, mean corpuscular volume, mean corpuscular hemoglobin, and mean corpuscular hemoglobin concentration. Iron(II) succinate increases serum ferritin, serum iron levels, and transferrin saturation, while decreasing total iron-binding capacity in iron-deficiency anemia rats. Iron(II) succinate reduces the elevated heart, spleen, and kidney coefficients, and increases the decreased liver coefficient in iron-deficiency anemia rats. Iron(II) succinate replenishes the depleted iron content in the liver and spleen of iron-deficiency anemia rats. Iron(II) succinate can be used for the research of iron-deficiency anemia .
    Iron(II) succinate
  • HY-W248118
    Pyrromethene 556

    PM556

    		 Fluorescent Dye Others
    Pyrromethene 556 (PM556) is a green-fluorescent polar tracer dye. It is used for investigations of membrane fusion, lysis, and gap-junctional communication and to detect volume changes in cells or liposomes.
    Pyrromethene 556
  • HY-134368
    Ap3A

    		Calcium Channel Cardiovascular Disease
    Ap3A is a vasoactive molecule that regulates intracellular Ca 2+ levels. Ap3A can promote the growth of vascular smooth muscle cells .
    Ap3A
  • HY-B0235R
    Trichlormethiazide (Standard)

    		Carbonic Anhydrase Reference Standards Metabolic Disease
    Trichlormethiazide (Standard) is the analytical standard of Trichlormethiazide. This product is intended for research and analytical applications. Trichlormethiazide is an orally active thiazide diuretic, with antihypertensive effect. Trichlormethiazide increases urine volume (UV), Na and K excretion and tends to improve the depressed creatinine clearance (CCRE) in acute renal failure rats model .
    Trichlormethiazide (Standard)
  • HY-18402
    2-(Methylthio)benzothiazole

    		Drug Derivative Cardiovascular Disease
    2-(Methylthio)benzothiazole is a derivative of 2-Mercaptobenzothiazole (HY-W017113). 2-(Methylthio)benzothiazole reduces heart rate, causes pericardial edema and deformity, delays cardiac maturation, decreases stroke volume and cardiac output, and leads to vascular structural defects in zebrafish larvae .
    2-(Methylthio)benzothiazole
  • HY-143321
    STING agonist-13

    		STING Cancer
    STING agonist-13 is a stimulator of interferon genes (STING) agonist, for cancer immunity via STING-mediated immune activation. STING agonist-13 can stimulate STING downstream signaling and promoting type I interferon immune responses. STING agonist-13 significantly decreases tumor volume and shows immunological memory-derived cancer inhibition .
    STING agonist-13
  • HY-DY1058
    2′,7′-Dichlorofluorescein diacetate (solution)

    		Fluorescent Dye Reactive Oxygen Species (ROS) Others
    2′,7′-Dichlorofluorescein diacetate (DCFH2-DA) (solution) is a cell-permeable fluorescent probe. 2′,7′-Dichlorofluorescein diacetate can be used to detect the generation of reactive oxygen intermediates and for assessing the overall oxidative stress in toxicological phenomenon .
    Solvent and concentration: DMSO: 10 mM
    The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
    2′,7′-Dichlorofluorescein diacetate (solution)
  • HY-D2706
    Cy3 Dextran (MW 3000)

    		Fluorescent Dye Others
    Cy3 Dextran (MW 3000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
    Cy3 Dextran (MW 3000)
  • HY-P4144
    Onvitrelin ucalontide

    Phor18-LHRH (338613); EP-100

    		 GnRH Receptor Cancer
    Onvitrelin ucalontide (Phor18-LHRH (338613); EP-100) is a luteinizing hormone-releasing hormone (LHRH) receptor ligand. Onvitrelin ucalontide binds to functional LHRH receptors on cancer cells and mediates targeted cytotoxicity. Onvitrelin ucalontide reduces tumor volume, weight and the number of viable tumor cells in xenograft models. Onvitrelin ucalontide can be used for the research of breast cancer, ovarian cancer and prostate cancer .
    Onvitrelin ucalontide
  • HY-D2460
    Dextran-CY5.5

    		Fluorescent Dye Cardiovascular Disease Cancer
    Dextran-CY5.5 is a CY5.5 (HY-D0924) labeled Dextran (HY-112624) conjugate. CY5.5 is a Cyanine dye (The excitation wavelength is usually 673 nm and the emission wavelength is 707 nm) that can be used for the labeling of proteins, antibodies and small molecular compounds. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander .
    Dextran-CY5.5
  • HY-105011A
    YM-358 hydrate potassium

    		Angiotensin Receptor Cardiovascular Disease
    YM-358 hydrate potassium is an orally active angiotensin II type 1 (AT1)-receptor antagonist. YM-358 hydrate potassium can decrease cardiac volume overload. YM-358 hydrate potassium can be used for the research of cardiovascular disease, such as hypertension .
    YM-358 hydrate potassium
  • HY-118605
    Aminometradine

    		Sodium Channel Chloride Channel Cardiovascular Disease Endocrinology
    Aminometradine is an orally active diuretic. Aminometradine increases urine volume and the excretion of sodium and chloride. Aminometradine can be used in studies of congestive heart failure .
    Aminometradine

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