Securitinine
Securitinine is a Securinega alkaloid. Securitinine can be derived from the wood of Japanese medicinal plant Securinega suffruticosa var.
For research use only. We do not sell to patients.
- CAS No.: 13861-71-7
- Formula: C14H17NO3
- Molecular Weight:247.29
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
>10 μM
Compound: 11
|
Cytotoxicity against human A549 cells after 48 hrs by SRB assay
Cytotoxicity against human A549 cells after 48 hrs by SRB assay
|
[PMID: 31082231] |
| BV-2 | IC50 |
31.5 μM
Compound: 11
|
Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced nitrite production after 24 hrs by Griess assay
Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced nitrite production after 24 hrs by Griess assay
|
[PMID: 31082231] |
| HCT-15 | IC50 |
>10 μM
Compound: 11
|
Cytotoxicity against human HCT15 cells after 48 hrs by SRB assay
Cytotoxicity against human HCT15 cells after 48 hrs by SRB assay
|
[PMID: 31082231] |
| SK-MEL-2 | IC50 |
>10 μM
Compound: 11
|
Cytotoxicity against human SK-MEL-2 cells after 48 hrs by SRB assay
Cytotoxicity against human SK-MEL-2 cells after 48 hrs by SRB assay
|
[PMID: 31082231] |
| SK-OV-3 | IC50 |
>10 μM
Compound: 11
|
Cytotoxicity against human SKOV3 cells after 48 hrs by SRB assay
Cytotoxicity against human SKOV3 cells after 48 hrs by SRB assay
|
[PMID: 31082231] |
Chemical Information
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CAS No. 13861-71-7
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Molecular Weight 247.29
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Formula C14H17NO3
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SMILES
O=C(O1)C=C2[C@@]13[C@@](C[C@@H](OC)CC4)([H])N4[C@](C3)([H])C=C2
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)