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ARS-1620 intermediate

ARS-1620 intermediate is an intermediate in the synthesis of a K-Ras^G12C inhibitor ARS1620 (HY-U00418).

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CAS No.: 1698027-20-1
Formula: C₁₇H₁₉BrClFN₄O₂
Molecular Weight:445.71

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

ARS-1620 intermediate Chemical Structure

CAS No.: 1698027-20-1

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Fluorescent Dye

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Biological Activity

Description

ARS-1620 intermediate is an intermediate in the synthesis of a K-Ras^G12C inhibitor ARS1620 (HY-U00418)^[1].

Chemical Information

CAS No. 1698027-20-1
Molecular Weight 445.71
Formula C₁₇H₁₉BrClFN₄O₂
SMILES

ClC1=C(Br)C(F)=C(N=CN=C2N3CCN(C(OC(C)(C)C)=O)CC3)C2=C1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Janes, M. R., et al., (2018). Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor. Cell, 172(3), 578–589.e17. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Chemical Information
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References

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