NAD+-d4
Based on 1 Customer Validation
NAD+-d4 is the deuterium-labeled NAD+ (HY-B0445). NAD+-d4 is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage.
For research use only. We do not sell to patients.
- Purity: 98.32%
- Formula: C21H23D4N7O14P2
- Molecular Weight:667.45
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 53-84-9
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Appearance Solid
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Molecular Weight 667.45
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Formula C21H23D4N7O14P2
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Color White to off-white
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SMILES
O[C@H]1[C@@H](O)[C@H]([N+]2=C([2H])C([2H])=C([2H])C(C(N)=O)=C2[2H])O[C@@H]1COP([O-])(OP(OC[C@@H]3[C@@H](O)[C@@H](O)[C@H](N4C5=NC=NC(N)=C5N=C4)O3)(O)=O)=O
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Synonyms
β-DPN-d4; β-NAD-d4; β-Nicotinamide Adenine Dinucleotide-d4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
H2O : 41.67 mg/mL (62.43 mM; Need ultrasonic and warming)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (252 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 1.4982 mL | 7.4912 mL | 14.9824 mL | 37.4560 mL |
| 5 mM | 0.2996 mL | 1.4982 mL | 2.9965 mL | 7.4912 mL | |
| 10 mM | 0.1498 mL | 0.7491 mL | 1.4982 mL | 3.7456 mL | |
| 15 mM | 0.0999 mL | 0.4994 mL | 0.9988 mL | 2.4971 mL | |
| 20 mM | 0.0749 mL | 0.3746 mL | 0.7491 mL | 1.8728 mL | |
| 25 mM | 0.0599 mL | 0.2996 mL | 0.5993 mL | 1.4982 mL | |
| 30 mM | 0.0499 mL | 0.2497 mL | 0.4994 mL | 1.2485 mL | |
| 40 mM | 0.0375 mL | 0.1873 mL | 0.3746 mL | 0.9364 mL | |
| 50 mM | 0.0300 mL | 0.1498 mL | 0.2996 mL | 0.7491 mL | |
| 60 mM | 0.0250 mL | 0.1249 mL | 0.2497 mL | 0.6243 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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