Thiamethoxam
Based on 1 publication(s) in Google Scholar
Thiamethoxam is a broad spectrum neonicotinoid insecticide.
For research use only. We do not sell to patients.
- Purity: 99.83%
- CAS No.: 153719-23-4
- Formula: C8H10ClN5O3S
- Molecular Weight:291.71
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Anti-Infection Compound Library
HY-L002
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Human Metabolite Library
HY-L123
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Heterocyclic Compound Library
HY-L138
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Bioactive Compound Library Max
HY-L181
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MCE Bioactive Compound Library
HY-L001V
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Bioactive Compound Library
HY-L001
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Pesticide Compound Library
HY-L183
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High-Throughput Bioactive Compound Library
HY-L205
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Mass Spectrometry Human Metabolite Library
HY-L215
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Environmental Pollutant Compound Library
HY-L247
Publications Citing Use of MedChemExpress (MCE) Thiamethoxam
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Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 153719-23-4
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Appearance Solid
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Molecular Weight 291.71
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Formula C8H10ClN5O3S
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Color Off-white to yellow
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SMILES
O=[N+](/N=C1N(CC2=CN=C(Cl)S2)COCN/1C)[O-]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications (1)
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Journal Impact Factor
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Most Recent
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ACS Environ Au
Machine Learning-Assisted Recognition of Environmental Sulfur-Containing Chemicals in Nontargeted Mass Spectrometry Analysis of Inadequate Mass Resolution. [Abstract]2025 Aug 5;5(6):573-582. PMID: 41277996
Solvent & Solubility
DMSO : ≥ 100 mg/mL (342.81 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.08 mg/mL (7.13 mM); Clear solution
This protocol yields a clear solution of ≥ 2.08 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (20.8 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.08 mg/mL (7.13 mM); Clear solution
This protocol yields a clear solution of ≥ 2.08 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (20.8 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL. * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (275 KB)
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SDS (550 KB)
- English - EN (550 KB)
- Français - FR (550 KB)
- Deutsch - DE (550 KB)
- Norwegian - NO (550 KB)
- Español - ES (550 KB)
- Swedish - SV (550 KB)
- Italian - IT (550 KB)
- Korean - KR (550 KB)
- Portuguese - PT (550 KB)
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Handling Instructions (2659 KB)
References
[1]. Lobson C, et al. Fate of thiamethoxam in mesocosms and response of the zooplankton community. Sci Total Environ. 2018 Oct 1;637-638:1150-1157. [Content Brief]
[2]. Ludicke JC, et al. Thiamethoxam impairs honey bee visual learning, alters decision times, and increases abnormal behaviors. Ecotoxicol Environ Saf. 2020 Apr 15;193:110367. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.4281 mL | 17.1403 mL | 34.2806 mL | 85.7016 mL |
| 5 mM | 0.6856 mL | 3.4281 mL | 6.8561 mL | 17.1403 mL | |
| 10 mM | 0.3428 mL | 1.7140 mL | 3.4281 mL | 8.5702 mL | |
| 15 mM | 0.2285 mL | 1.1427 mL | 2.2854 mL | 5.7134 mL | |
| 20 mM | 0.1714 mL | 0.8570 mL | 1.7140 mL | 4.2851 mL | |
| 25 mM | 0.1371 mL | 0.6856 mL | 1.3712 mL | 3.4281 mL | |
| 30 mM | 0.1143 mL | 0.5713 mL | 1.1427 mL | 2.8567 mL | |
| 40 mM | 0.0857 mL | 0.4285 mL | 0.8570 mL | 2.1425 mL | |
| 50 mM | 0.0686 mL | 0.3428 mL | 0.6856 mL | 1.7140 mL | |
| 60 mM | 0.0571 mL | 0.2857 mL | 0.5713 mL | 1.4284 mL | |
| 80 mM | 0.0429 mL | 0.2143 mL | 0.4285 mL | 1.0713 mL | |
| 100 mM | 0.0343 mL | 0.1714 mL | 0.3428 mL | 0.8570 mL |
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