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Cat. No.: HY-143658

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SH498

SH498, a novel Bmi-1-mediated antitumor agent, shows potent antiproliferative activity.

For research use only. We do not sell to patients.

CAS No.: 2125724-38-9
Formula: C₂₇H₂₅F₃N₂O₄
Molecular Weight:498.49

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

SH498 Chemical Structure

CAS No.: 2125724-38-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

SH498, a novel Bmi-1-mediated antitumor agent, shows potent antiproliferative activity.

Chemical Information

CAS No. 2125724-38-9
Molecular Weight 498.49
Formula C₂₇H₂₅F₃N₂O₄
SMILES

O=C(C(C=C1CCC2C3(C)C)=C(OC)C=C1[C@@]2(C)C=C(C#N)C3=O)NC4=CC=CC(OC(F)(F)F)=C4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Yang LF, et al. Synthesis of Cyanoenone-Modified Diterpenoid Analogs as Novel Bmi-1-Mediated Antitumor Agents. ACS Med Chem Lett. 2018 Sep 27;9(11):1105-1110. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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