SMI-16a (Standard)
SMI-16a (Standard) is the analytical standard of SMI-16a (HY-101947). This product is intended for research and analytical applications. SMI-16a is a selective Pim kinase inhibitor with IC50 values of 0.15, 0.02 and 48 μM for Pim1, Pim2 and PC3 cells, respectively.
For research use only. We do not sell to patients.
- CAS No.: 587852-28-6
- Formula: C13H13NO3S
- Molecular Weight:263.31
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 587852-28-6
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Molecular Weight 263.31
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Formula C13H13NO3S
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SMILES
O=C(NC/1=O)SC1=C\C2=CC=C(OCCC)C=C2
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Synonyms
PIM1/2 Kinase Inhibitor VI (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Xia Z, et al. Synthesis and evaluation of novel inhibitors of Pim-1 and Pim-2 protein kinases. J Med Chem. 2009 Jan 8;52(1):74-86. [Content Brief]
[2]. Hiasa M, et al. Pim-2 kinase is an important target of treatment for tumor progression and bone loss in myeloma. Leukemia. 2015 Jan;29(1):207-17. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)