SphK2-IN-1
Based on 1 Customer Validation
SphK2-IN-1 is a SphK2 inhibitor (IC50: 0.359 μM). SphK2-IN-1 can be used in the research of cancer, inflammation, neurological and cardiovascular disorders.
For research use only. We do not sell to patients.
- Purity: 99.61%
- CAS No.: 2927429-64-7
- Formula: C23H22ClF3N8O
- Molecular Weight:518.92
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
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SphK2 0.359 μM (IC50) |
SphK2-IN-1 (compound 25b, 125 µM, 24 h) inhibits cell viability against U-251 MG human glioblastoma cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:U-251 MG human glioblastoma cells
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Concentration:125 µM
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Incubation Time:24 h
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Result:Decreased cell viability by more than 80%.
Chemical Information
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CAS No. 2927429-64-7
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Appearance Solid
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Molecular Weight 518.92
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Formula C23H22ClF3N8O
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Color White to off-white
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SMILES
N=C(N1CCC[C@H]1C2=NC(C3=CC=C(C=C3)CN4C=C(N=N4)C5=CC=C(C=C5)C(F)(F)F)=NO2)N.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (271 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)