1. Immunology/Inflammation
  2. SphK
  3. SphK2-IN-1

SphK2-IN-1 

Cat. No.: HY-151350
Handling Instructions

SphK2-IN-1 is a SphK2 inhibitor (IC50: 0.359 μM). SphK2-IN-1 can be used in the research of cancer, inflammation, neurological and cardiovascular disorders.

For research use only. We do not sell to patients.

SphK2-IN-1 Chemical Structure

SphK2-IN-1 Chemical Structure

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Description

SphK2-IN-1 is a SphK2 inhibitor (IC50: 0.359 μM). SphK2-IN-1 can be used in the research of cancer, inflammation, neurological and cardiovascular disorders[1].

IC50 & Target[1]

SphK2

0.359 μM (IC50)

In Vitro

SphK2-IN-1 (compound 25b, 125 µM, 24 h) inhibits cell viability against U-251 MG human glioblastoma cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: U-251 MG human glioblastoma cells
Concentration: 125 µM
Incubation Time: 24 h
Result: Decreased cell viability by more than 80%.
Molecular Weight

518.92

Formula

C23H22ClF3N8O

SMILES

N=C(N1CCC[[email protected]]1C2=NC(C3=CC=C(C=C3)CN4C=C(N=N4)C5=CC=C(C=C5)C(F)(F)F)=NO2)N.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Product Name:
SphK2-IN-1
Cat. No.:
HY-151350
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