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SSOe26 sodium

SSOe26 sodium is a 15mer antisense oligonucleotide targeting?HER4. SSOe26 sodium induces exon 26 skipping, leading to the generation of a novel mRNA transcript that excludes exon 26 (CYT2 isoform). SSOe26 sodium decreases tumour growth in mouse xenografts.

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  • SSOe26 sodium Chemical Structure
    SSOe26 sodium Chemical Structure
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  • SSOe26 sodium Chemical Structure
    SSOe26 sodium Chemical Structure 5'-(L)T(m)U(L)A(m)C(m)U(L)C(m)C(m)U(L)G(m)A(m)C(L)A(m)U(L)G(L)G-3' (L=LNA, m=2'-O-methyl)
    1/16
  • 5'-(L)T(m)U(L)A(m)C(m)U(L)C(m)C(m)U(L)G(m)A(m)C(L)A(m)U(L)G(L)G-3' (L=LNA, m=2'-O-methyl)