2. Protein Tyrosine Kinase/RTK
  3. VEGFR
  4. SU5208

SU5208 inhibits vascular endothelial growth factor receptor-2 (VEGFR2).

For research use only. We do not sell to patients.

SU5208 Chemical Structure

SU5208 Chemical Structure

CAS No. : 62540-08-3

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5 mg USD 290 In-stock
10 mg USD 460 In-stock
50 mg USD 995 In-stock
100 mg USD 1390 In-stock
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Based on 1 publication(s) in Google Scholar

SU5208 Related Antibodies

Top Publications Citing Use of Products

View All VEGFR Isoform Specific Products:

View All Isoforms
VEGFR1/Flt-1 VEGFR2/KDR/Flk-1 VEGFR3/Flt-4

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Description

SU5208 inhibits vascular endothelial growth factor receptor-2 (VEGFR2)[1].

IC50 & Target[1]

VEGFR2

 

Molecular Weight

227.28

Formula

C13H9NOS
CAS No.
Appearance

Solid

Color

Yellow to orange

SMILES

O=C1NC2=C(C=CC=C2)/C1=C/C3=CC=CS3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (439.99 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.3999 mL 21.9993 mL 43.9986 mL
5 mM 0.8800 mL 4.3999 mL 8.7997 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.3999 mL 21.9993 mL 43.9986 mL 109.9965 mL
5 mM 0.8800 mL 4.3999 mL 8.7997 mL 21.9993 mL
10 mM 0.4400 mL 2.1999 mL 4.3999 mL 10.9996 mL
15 mM 0.2933 mL 1.4666 mL 2.9332 mL 7.3331 mL
20 mM 0.2200 mL 1.1000 mL 2.1999 mL 5.4998 mL
25 mM 0.1760 mL 0.8800 mL 1.7599 mL 4.3999 mL
30 mM 0.1467 mL 0.7333 mL 1.4666 mL 3.6665 mL
40 mM 0.1100 mL 0.5500 mL 1.1000 mL 2.7499 mL
50 mM 0.0880 mL 0.4400 mL 0.8800 mL 2.1999 mL
60 mM 0.0733 mL 0.3667 mL 0.7333 mL 1.8333 mL
80 mM 0.0550 mL 0.2750 mL 0.5500 mL 1.3750 mL
100 mM 0.0440 mL 0.2200 mL 0.4400 mL 1.1000 mL
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SU5208 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SU520862540-08-3SU 5208SU-5208VEGFRVascular endothelial growth factor receptorInhibitorinhibitorinhibit

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