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Cat. No.: HY-162064

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T-1-MBHEPA

T-1-MBHEPA is a potent inhibitor of VEGFR-2, with the IC₅₀ value of 0.121±0.051 μM. T-1-MBHEPA has anti-tumor and anti-angiogenic effect.

For research use only. We do not sell to patients.

Formula: C₂₅H₂₅N₇O₄
Molecular Weight:487.51

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

T-1-MBHEPA Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

T-1-MBHEPA is a potent inhibitor of VEGFR-2, with the IC₅₀ value of 0.121±0.051 μM. T-1-MBHEPA has anti-tumor and anti-angiogenic effect^[1].

IC₅₀ & Target

VEGFR-2

0.121 μM (IC₅₀)

All VEGFR Isoforms :

Chemical Information

Molecular Weight 487.51
Formula C₂₅H₂₅N₇O₄
SMILES

O=C(C(N(C)C=N1)=C1N2C)N(CC(NC3=CC=C(/C(C)=N/NC(C4=CC=CC(C)=C4)=O)C=C3)=O)C2=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Ibrahim H Eissa, et al. Computer-assisted drug discovery (CADD) of an anti-cancer derivative of the theobromine alkaloid inhibiting VEGFR-2. Saudi Pharm J. 2023 Dec;31(12):101852. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration Concentration

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Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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