T-1-MBHEPA
T-1-MBHEPA is a potent inhibitor of VEGFR-2, with the IC50 value of 0.121±0.051 μM. T-1-MBHEPA has anti-tumor and anti-angiogenic effect.
For research use only. We do not sell to patients.
- Formula: C25H25N7O4
- Molecular Weight:487.51
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All VEGFR Isoforms
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Biological Activity
Description
IC50 & Target
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VEGFR-2 0.121 μM (IC50) |
Chemical Information
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Molecular Weight 487.51
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Formula C25H25N7O4
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SMILES
O=C(C(N(C)C=N1)=C1N2C)N(CC(NC3=CC=C(/C(C)=N/NC(C4=CC=CC(C)=C4)=O)C=C3)=O)C2=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)