T.cruzi-IN-4
T.cruzi-IN-4 (Compound 21) is an anti-parasitic agent. T.cruzi-IN-4 inhibits the trypomastigote and amastigote form of Trypanosoma cruzi with IC50 of 0.033 μM (120 h), T.cruzi-IN-4 inhibits the promastigote and amastigote form of Leishmania infantum with IC50 of 28.74 and 61.82 μM. T.cruzi-IN-4 inhibits Leishmania amazonensis promastigote form with IC50 of 18.38 μM.
For research use only. We do not sell to patients.
- Formula: C13H9N5O4
- Molecular Weight:299.24
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Parasite Isoforms
More
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| L929 | CC50 |
256.6 μM
Compound: 21
|
Cytotoxicity against mouse L929 cells assessed as inhibition of cell viability measured after 120 hrs
Cytotoxicity against mouse L929 cells assessed as inhibition of cell viability measured after 120 hrs
|
[PMID: 38964519] |
| RAW264.7 | CC50 |
25.73 μM
Compound: 21
|
Cytotoxicity against mouse RAW264.7 cells measured after 48 hrs
Cytotoxicity against mouse RAW264.7 cells measured after 48 hrs
|
[PMID: 38964519] |
Chemical Information
-
Molecular Weight 299.24
-
Formula C13H9N5O4
-
SMILES
O=C(C1=NC2=CC=CC=C2N1)N/N=C/C3=CC=C([N+]([O-])=O)O3
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)