TAU-IN-6
TAU-IN-6 (Compound 13) is a Tau protein misfolding and aggregation inhibitor. TAU-IN-6 inhibits stress granules composed of tau and TIA1. TAU-IN-6 is applicable for Alzheimer's disease research.
For research use only. We do not sell to patients.
- CAS No.: 3083792-74-6
- Formula: C24H21F7N4O2
- Molecular Weight:530.44
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
TAU-IN-6 inhibits arsenite-induced tau/TIA1 stress granules in SH-SY5Y-tT1 cells with an IC50 of less than 1000 nM[1].
TAU-IN-6 inhibits thapsigargin-induced tau/TIA1 stress granules in SH-SY5Y-tT1 cells, with an IC50 of less than 500 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3083792-74-6
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Molecular Weight 530.44
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Formula C24H21F7N4O2
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SMILES
FC(F)(C1=C(F)C=CC(C2=NC(CN3[C@@H](C[C@@H](CC3)C(NC4=CC(C(F)(F)F)=CC=C4)=O)C)=NO2)=C1)F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
TAU-IN-6 Related Classifications
HY-185357 Related Classifications
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