TCS 401 free base
Based on 2 publication(s) in Google Scholar
TCS 401 free base is a selective inhibitor of protein tyrosine phosphatase 1B (PTP1B).
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 243967-42-2
- Fòrmula: C10H10N2O5S
- Peso molecular:270.26
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Actividad biológica
-
Chemical Information
- Pureza y Documentación
- Referencias
-
Help & FAQs
Publications Citing Use of MedChemExpress (MCE) TCS 401 free base
More
Customer Validation & Images
-
WB
Actividad biológica
Descripciòn
Chemical Information
-
No. CAS 243967-42-2
-
Peso molecular 270.26
-
Fòrmula C10H10N2O5S
-
SMILES
O=C(C(NC1=C(C(O)=O)C(CCNC2)=C2S1)=O)O
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (2)
-
Journal Impact Factor
-
Most Recent
-
J Tissue Eng Regen Med
Inhibition of protein-tyrosine phosphatase 1B phosphorylation enhances early adhesion of mesenchymal stem cells to facilitate fabrication of tissue-engineered bone. [Abstract]2020 Apr;14(4):575-587. PMID: 32061178
TCS 401 free base purchased from MedChemExpress. Usage Cited in: J Tissue Eng Regen Med. 2020 Apr;14(4):575-587. [Abstract]
The activation of Src by treatment with the 152RM peptide is reversed by pretreatment with the PTP1B inhibitor TCS-401, and the increased phosphorylation of β-catenin Y654 by treatment with the 152RM peptide is reduced by pretreatment with the Src inhibitor bosutinib.
-
In Vitro Cell Dev Biol Anim
Angiotensin II induces apoptosis of cardiac microvascular endothelial cells via regulating PTP1B/PI3K/Akt pathway. [Abstract]2019 Dec;55(10):801-811. PMID: 31502193
Pureza y Documentación
Referencias
[1]. Du ZD, et al. Protein tyrosine phosphatase 1B regulates the activity of retinal pigment epithelial cells. Mol Vis. 2015 May 1;21:523-31. [Content Brief]
[2]. Ponnusamy M, et al. Necrotic renal epithelial cell inhibits renal interstitial fibroblast activation: role of protein tyrosine phosphatase 1B. Am J Physiol Renal Physiol. 2013 Mar 15;304(6):F698-709. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
TCS 401 free base Related Classifications
HY-12312A Related Classifications
Powered by Bioz