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Cat. No.: HY-111046

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Thailandolide B

Thailandolide B is a merodrimane-type meroterpenoid fungal (fungal) metabolite that exhibits insecticidal activity against silkworm (Bombyx mori) larvae (LD₅₀ = 10 μg/g diet). Thailandolide B can be used in research on insecticidal natural products.

For research use only. We do not sell to patients.

CAS No.: 944726-62-9
Formula: C₂₇H₃₄O₈
Molecular Weight:486.55

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Thailandolide B Chemical Structure

CAS No.: 944726-62-9

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

In Vivo

Thailandolide B (10 μg/g diet; p.o.; single administration; 24 h) exhibits insecticidal activity against third-instar larvae of the silkworm (Bombyx mori), with an LD₅₀ of 10 μg/g diet^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

Third-instar silkworm larvae (artificial diet assay; 30 larvae per dose; instar and sex of insects noted in Animal Model)^[3]
Dosage:

10 μg/g diet (LD₅₀)
Administration:

p.o. (mixed into artificial diet); single administration; 24 h
Result:

Exhibited insecticidal activity with an LD₅₀ of 10 μg/g of diet.

Related Protocols :

Acute Systemic Toxicity Study

Chemical Information

CAS No. 944726-62-9
Molecular Weight 486.55
Formula C₂₇H₃₄O₈
SMILES

C[C@@]12[C@]3([H])[C@@](OC4=CC(O)=C(C(O[C@@H]([C@@H]5OC(C)=O)C)=O)C5=C4C3)([C@H](C[C@@]1([H])C(C)(C(CC2)=O)C)O)C
Structure Classification
- Terpenoids
- Other Terpenoids
Initial Source
- Microorganisms
Talaromyces thailandiasis
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Dethoup T, et al. Merodrimanes and other constituents from Talaromyces thailandiasis. Journal of natural products. 2007 Jul;70(7):1200-2.

[2]. El-Elimat T, et al. Coumarins, dihydroisocoumarins, a dibenzo-α-pyrone, a meroterpenoid, and a merodrimane from Talaromyces amestolkiae. Tetrahedron Lett. 2021 May 25;72:153067.

[3]. Hayashi H, et al. A new meroterpenoid, chrodrimanin C, from YO-2 of Talaromyces sp. Bioscience, biotechnology, and biochemistry. 2012;76(4):745-8.

[4]. Hayashi H, et al. New chrodrimanin congeners, chrodrimanins D-H, from YO-2 of Talaromyces sp. Bioscience, biotechnology, and biochemistry. 2012;76(9):1765-8.

[5]. Kuml D, et al. Spiculisporic acid E, a new spiculisporic acid derivative and ergosterol derivatives from the marine-sponge associated fungus Talaromyces trachyspermus (KUFA 0021). Natural product communications. 2014 Aug;9(8):1147-50.

[6]. Nonaka K, et al. Induced production of BE-31405 by co-culturing of Talaromyces siamensis FKA-61 with a variety of fungal strains. The Journal of antibiotics. 2015 Sep;68(9):573-8. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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