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Cat. No.: HY-110244R

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Tilfrinib (Standard)

Tilfrinib (Standard) is the analytical standard of Tilfrinib (HY-110244). This product is intended for research and analytical applications. Tilfrinib (compound 4f) is a potent and selective Brk/PTK6 inhibitor with an IC₅₀ value of 3.15 nM for Brk. Tilfrinib shows good anti-proliferative activity and has potential of anti-tumour.

For research use only. We do not sell to patients.

CAS No.: 1600515-49-8
Formula: C₁₇H₁₃N₃O
Molecular Weight:275.30

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Tilfrinib (Standard) Chemical Structure

CAS No.: 1600515-49-8

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 1600515-49-8
Molecular Weight 275.30
Formula C₁₇H₁₃N₃O
SMILES

OC1=CC=CC(NC2=C3C4=CC=CC=C4NC3=NC=C2)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Zhang Q, Liu S, et al. ETV4 mediated tumor-associated neutrophil recruitment promotes lymphangiogenesis and lymphatic metastasis of bladder cancer[J]. 2022.

[2]. Mahmoud KA, et al. Discovery of 4-anilino α-carbolines as novel Brk inhibitors. Bioorg Med Chem Lett. 2014 Apr 15;24(8):1948-51. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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