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Referencia número: HY-170899

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TLR7 agonist 28

TLR7 agonist 28 (compound 3) is a potent TLR7 agonist. TLR7 agonist 28 can conjugat to antitumor monoclonal antibodies (mAbs) for cancer immunotherapy.

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No. CAS: 1801518-98-8
Fòrmula: C₂₆H₂₅N₉O₇
Peso molecular:575.53

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

TLR7 agonist 28 Chemical Structure

No. CAS: 1801518-98-8

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Actividad biológica

Descripciòn

TLR7 agonist 28 (compound 3) is a potent TLR7 agonist. TLR7 agonist 28 can conjugat to antitumor monoclonal antibodies (mAbs) for cancer immunotherapy^[1].

IC₅₀ & Target^[1]

TLR7

Ver todos los productos específicos de isoformas Toll-like Receptor (TLR) :

Chemical Information

No. CAS 1801518-98-8
Peso molecular 575.53
Fòrmula C₂₆H₂₅N₉O₇
SMILES

O=C(N(C1=NC(OCCOC)=N2)CC3=CC=C(C=C3)/C=N/NC4=CC=C(C=N4)C(ON5C(CCC5=O)=O)=O)NC1=C2N
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Gadd AJ, et al. Targeted Activation of Toll-Like Receptors: Conjugation of a Toll-Like Receptor 7 Agonist to a Monoclonal Antibody Maintains Antigen Binding and Specificity. Bioconjug Chem. 2015 Aug 19;26(8):1743-52. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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TLR7 agonist 28

Ver todos los productos específicos de isoformas Toll-like Receptor (TLR)

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

TLR7 agonist 28 Related Classifications

HY-170899 Related Classifications