1. Metabolic Enzyme/Protease
  2. HIF/HIF Prolyl-Hydroxylase
  3. TM6089

TM6089 

Cat. No.: HY-118543
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TM6089 is a unique Prolyl Hydroxylase (PHD) inhibitor which stimulates HIF activity without iron chelation and induces angiogenesis and exerts organ protection against ischemia. Local administration of TM6089 enhances angiogenesis, and oral administration stimulates HIF activity in transgenic rats expressing a hypoxia-responsive reporter vector.

For research use only. We do not sell to patients.

TM6089 Chemical Structure

TM6089 Chemical Structure

CAS No. : 863421-32-3

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Description

TM6089 is a unique Prolyl Hydroxylase (PHD) inhibitor which stimulates HIF activity without iron chelation and induces angiogenesis and exerts organ protection against ischemia. Local administration of TM6089 enhances angiogenesis, and oral administration stimulates HIF activity in transgenic rats expressing a hypoxia-responsive reporter vector[1].

Molecular Weight

306.34

Formula

C₁₃H₁₄N₄O₃S

CAS No.

863421-32-3

SMILES

O=C1N(C(C(C(CSC2=NC=CC=C2)=O)=C(N1C)N)=O)C

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Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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TM6089
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