TTBK1-IN-3
TTBK1-IN-3 (Compound 18) is a potent inhibitor of TTBK1, with a biochemical IC₅₀ of 18 nM and a cellular IC₅₀ of 259 nM. TTBK1-IN-3 can be used for research on Alzheimer's disease.
For research use only. We do not sell to patients.
- CAS No.: 2735015-52-6
- Formula: C16H16N6O
- Molecular Weight:308.34
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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TTBK1 18 nM (IC50) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | IC50 |
0.14 μM
Compound: 18
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Cytotoxicity against human HepG2 cells in glucose containing media incubated for 72 hrs by celltiter-glo luminescent cell viability assay
Cytotoxicity against human HepG2 cells in glucose containing media incubated for 72 hrs by celltiter-glo luminescent cell viability assay
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[PMID: 33944571] |
| HepG2 | IC50 |
0.18 μM
Compound: 18
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Cytotoxicity against human HepG2 cells in galactose containing media incubated for 72 hrs by celltiter-glo luminescent cell viability assay
Cytotoxicity against human HepG2 cells in galactose containing media incubated for 72 hrs by celltiter-glo luminescent cell viability assay
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[PMID: 33944571] |
Chemical Information
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CAS No. 2735015-52-6
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Molecular Weight 308.34
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Formula C16H16N6O
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SMILES
CC[C@](C)(O)C#CC1=NC=C2C=NN(C3=NC(N)=NC=C3)C2=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
TTBK1-IN-3 Related Classifications
HY-157310 Related Classifications
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