Koenimbine
Koenimbine is an anticancer agent that can be obtained from the leaves and fruits of Murraya koenigii. Koenimbine can induce apoptosis and necrosis in HT-29 and SW48 cells. Koenimbine can be used in the research of cancer.
For research use only. We do not sell to patients.
- CAS No.: 21087-98-9
- Formula: C19H19NO2
- Molecular Weight:293.36
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| B16-4A5 | IC50 |
1.2 μM
Compound: 13
|
Inhibition of theophylline-induced melanogenesis in mouse B16-4A5 cells after 72 hrs by spectrophotometric analysis relative to control
Inhibition of theophylline-induced melanogenesis in mouse B16-4A5 cells after 72 hrs by spectrophotometric analysis relative to control
|
[PMID: 23376010] |
| DU-145 | IC50 |
0.2 μM
Compound: 35
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Antiproliferative activity against human DU-145 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
Antiproliferative activity against human DU-145 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
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[PMID: 34838335] |
| HCT-116 | IC50 |
0.2 μM
Compound: 35
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Antiproliferative activity against human HCT-116 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
Antiproliferative activity against human HCT-116 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
|
[PMID: 34838335] |
| HeLa | IC50 |
0.2 μM
Compound: 35
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Antiproliferative activity against human HeLa cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
Antiproliferative activity against human HeLa cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
|
[PMID: 34838335] |
| HepG2 | IC50 |
0.2 μM
Compound: 35
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Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
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[PMID: 34838335] |
| OVCAR-3 | IC50 |
0.2 μM
Compound: 35
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Antiproliferative activity against human OVCAR-3 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
Antiproliferative activity against human OVCAR-3 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
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[PMID: 34838335] |
| PA-1 | IC50 |
0.2 μM
Compound: 35
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Antiproliferative activity against human PA-1 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
Antiproliferative activity against human PA-1 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
|
[PMID: 34838335] |
Chemical Information
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CAS No. 21087-98-9
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Molecular Weight 293.36
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Formula C19H19NO2
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SMILES
CC1=CC2=C(NC3=C2C=C(C=C3)OC)C4=C1OC(C)(C=C4)C
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Koenimbine Related Classifications
HY-W727999 Related Classifications
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