MZ82
MZ82, Ko 143 (HY-10010) derivative, is a ATP-binding cassette subfamily G member 2 (ABCG2/BCRP) inhibitor with the IC50 of ~23 nM. MZ82 not only shows greatly improved metabolic stability over Ko 143 (HY-10010) in liver microsomes but also in mice, and is able to penetrate into the brain.
For research use only. We do not sell to patients.
- CAS No.: 2944457-11-6
- Formula: C26H29N3O3
- Molecular Weight:431.53
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 2944457-11-6
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Molecular Weight 431.53
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Formula C26H29N3O3
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SMILES
O=C1N[C@@H](CC2=CC=CC=C2)C(N3[C@@H](CC(C)C)C4=C(C5=CC=C(OC)C=C5N4)C[C@H]31)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)