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Cat. No.: HY-145346

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NLG802

Name: NLG802
Brand: MedChemExpress
SKU: HY-145346
Price: 125.00 USD
Availability: InStock
Rating: 5 (1 reviews)

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Based on 1 Customer Validation

NLG802 is a proagent of indoximod, an orally active indoleamine 2,3-dioxygenase (IDO) inhibitor.

For research use only. We do not sell to patients.

Purity: 98.77%
CAS No.: 2071683-99-1
Formula: C₂₀H₃₀ClN₃O₃
Molecular Weight:395.92

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

NLG802 Chemical Structure

CAS No.: 2071683-99-1

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Clinical Trial
Chemical Information
Solvent & Solubility
- In Vitro
Purity & Documentation
References
Help & FAQs
Classifications
Bioz

Biological Activity

Description

NLG802 is a proagent of indoximod, an orally active indoleamine 2,3-dioxygenase (IDO) inhibitor.

All Indoleamine 2,3-Dioxygenase (IDO) Isoforms :

Clinical Trial

NCT Number	Sponsor	Condition	Start Date	Phase A549
NCT01329991	Plexxikon\|		2011-05	PHASE1

Chemical Information

CAS No. 2071683-99-1
Appearance Solid
Molecular Weight 395.92
Formula C₂₀H₃₀ClN₃O₃
Color White to off-white
SMILES

CC(C)C[C@H](N)C(N[C@@H](C(OCC)=O)CC1=CN(C)C2=CC=CC=C12)=O.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility

In Vitro:

DMSO : 250 mg/mL (631.44 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

2.5258 mL

12.6288 mL

25.2576 mL

5 mM

0.5052 mL

2.5258 mL

5.0515 mL

10 mM

0.2526 mL

1.2629 mL

2.5258 mL

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Dilution Calculator

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Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Kumar S, et al. Discovery of indoximod prodrugs and characterization of clinical candidate NLG802. Eur J Med Chem. 2020 Jul 15;198:112373. [Content Brief]

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
DMSO	1 mM	2.5258 mL	12.6288 mL	25.2576 mL	63.1441 mL
	5 mM	0.5052 mL	2.5258 mL	5.0515 mL	12.6288 mL
	10 mM	0.2526 mL	1.2629 mL	2.5258 mL	6.3144 mL
	15 mM	0.1684 mL	0.8419 mL	1.6838 mL	4.2096 mL
	20 mM	0.1263 mL	0.6314 mL	1.2629 mL	3.1572 mL
	25 mM	0.1010 mL	0.5052 mL	1.0103 mL	2.5258 mL
	30 mM	0.0842 mL	0.4210 mL	0.8419 mL	2.1048 mL
	40 mM	0.0631 mL	0.3157 mL	0.6314 mL	1.5786 mL
	50 mM	0.0505 mL	0.2526 mL	0.5052 mL	1.2629 mL
	60 mM	0.0421 mL	0.2105 mL	0.4210 mL	1.0524 mL
	80 mM	0.0316 mL	0.1579 mL	0.3157 mL	0.7893 mL
	100 mM	0.0253 mL	0.1263 mL	0.2526 mL	0.6314 mL

Bioz

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MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- Description
- Clinical Trial
Chemical Information
Solvent & Solubility
- In Vitro
Purity & Documentation
References

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

Product Name:
CAS No.:
Species:
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Quantity:

NLG802

All Indoleamine 2,3-Dioxygenase (IDO) Isoforms

Biological Activity

Description

Clinical Trial

Chemical Information

Solvent & Solubility

In Vitro:

Purity & Documentation

References

Help & FAQs

Complete Stock Solution Preparation Table

NLG802 Related Classifications

HY-145346 Related Classifications

Bioz

Keywords

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