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Cat. No.: HY-117556

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U-104489

U-104489 is a HIV-1 inhibitor with the K_i values of 0.13, 0.12 and ＞ 100 μM aganist HIV-1 RT p66/p51 wild type (G190), G190A and G190E, respectively.

For research use only. We do not sell to patients.

CAS No.: 177577-60-5
Formula: C₂₆H₃₆N₆O₃S
Molecular Weight:512.67

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

U-104489 Chemical Structure

CAS No.: 177577-60-5

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

U-104489 is a HIV-1 inhibitor with the K_i values of 0.13, 0.12 and ＞ 100 μM aganist HIV-1 RT p66/p51 wild type (G190), G190A and G190E, respectively^[1].

All HIV Isoforms :

Chemical Information

CAS No. 177577-60-5
Molecular Weight 512.67
Formula C₂₆H₃₆N₆O₃S
SMILES

O=C(N1CCC(CC1)N(CC)C2=NC=CC=C2NC(C)(C)C)C3=CC4=C(N3)C=CC(NS(=O)(C)=O)=C4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Fan N, et al. A drug resistance mutation in the inhibitor binding pocket of human immunodeficiency virus type 1 reverse transcriptase impairs DNA synthesis and RNA degradation. Biochemistry. 1996;35(30):9737-9745. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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U-104489

All HIV Isoforms