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Cat. No.: HY-103341

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UCM707

UCM707, a potent and selective inhibitor of endocannabinoid uptake, potentiates hypokinetic and antinociceptive effects of Anandamide.

For research use only. We do not sell to patients.

CAS No.: 390824-20-1
Formula: C₂₅H₃₇NO₂
Molecular Weight:383.57

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (259 KB)

UCM707 Chemical Structure

CAS No.: 390824-20-1

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
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Bioz

Biological Activity

Description

UCM707, a potent and selective inhibitor of endocannabinoid uptake, potentiates hypokinetic and antinociceptive effects of Anandamide^[1].

All Cannabinoid Receptor Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
U-937	IC₅₀	0.8 μM Compound: 42	Concentration required to inhibit anandamide uptake in U937 cell line Concentration required to inhibit anandamide uptake in U937 cell line	[PMID: 16078824]
U-937	IC₅₀	0.8 μM Compound: 5	Inhibition of [3H]anandamide transport(ANT) in human lymphoma U937 cell Inhibition of [3H]anandamide transport(ANT) in human lymphoma U937 cell	[PMID: 12672252]
U-937	IC₅₀	0.8 μM Compound: 9	Ability to inhibit [3H]anandamide uptake in human lymphoma U937 cells Ability to inhibit [3H]anandamide uptake in human lymphoma U937 cells	[PMID: 11741470]
U-937	IC₅₀	1.46 μM Compound: UCM707	Inhibition of [ethanol-amine-1-3H]AEA uptake in human U937 cells preincubated for 15 mins measured 15 mins post AEA addition by liquid scintillation counting Inhibition of [ethanol-amine-1-3H]AEA uptake in human U937 cells preincubated for 15 mins measured 15 mins post AEA addition by liquid scintillation counting	[PMID: 24972328]
U-937	IC₅₀	7.24 μM Compound: UCM707	Inhibition of FAAH-mediated [ethanol-amine-1-3H]AEA hydrolysis in human U937 cells preincubated for 15 mins measured 15 mins post AEA addition by liquid scintillation counting Inhibition of FAAH-mediated [ethanol-amine-1-3H]AEA hydrolysis in human U937 cells preincubated for 15 mins measured 15 mins post AEA addition by liquid scintillation counting	[PMID: 24972328]

Chemical Information

CAS No. 390824-20-1
Molecular Weight 383.57
Formula C₂₅H₃₇NO₂
SMILES

CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(NCC1=COC=C1)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (259 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Eva de Lago, et al. UCM707, a potent and selective inhibitor of endocannabinoid uptake, potentiates hypokinetic and antinociceptive effects of anandamide. Eur J Pharmacol. 2002 Aug 2;449(1-2):99-103. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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Purity & Documentation
References

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UCM707

High-Throughput Bioactive Compound Library

All Cannabinoid Receptor Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

UCM707 Related Classifications

HY-103341 Related Classifications