Udonitrectag
Based on 1 Customer Validation
Udonitrectag (REC 0559) is a nerve growth factor peptide mimetic and a TrkA receptor binder. Udonitrectag binds to the TrkA receptor, thereby mimicking anti-Apoptotic activity and corneal trophic activity. Udonitrectag promotes the healing of corneal epithelium and stroma. Udonitrectag is applicable to research related to neurotrophic keratitis.
For research use only. We do not sell to patients.
- Purity: 98.81%
- CAS No.: 1458063-04-1
- Formula: C20H19NO5
- Molecular Weight:353.37
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
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TrkA |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 1458063-04-1
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Appearance Solid
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Molecular Weight 353.37
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Formula C20H19NO5
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Color White to off-white
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SMILES
O=C([C@H]1O[C@]2([H])[C@@H](CC3=CC=CC=C3)N(CC4=CC=CC=C4)C([C@@]1([H])O2)=O)O
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Synonyms
REC 0559
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 250 mg/mL (707.47 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (279 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.8299 mL | 14.1495 mL | 28.2990 mL | 70.7474 mL |
| 5 mM | 0.5660 mL | 2.8299 mL | 5.6598 mL | 14.1495 mL | |
| 10 mM | 0.2830 mL | 1.4149 mL | 2.8299 mL | 7.0747 mL | |
| 15 mM | 0.1887 mL | 0.9433 mL | 1.8866 mL | 4.7165 mL | |
| 20 mM | 0.1415 mL | 0.7075 mL | 1.4149 mL | 3.5374 mL | |
| 25 mM | 0.1132 mL | 0.5660 mL | 1.1320 mL | 2.8299 mL | |
| 30 mM | 0.0943 mL | 0.4716 mL | 0.9433 mL | 2.3582 mL | |
| 40 mM | 0.0707 mL | 0.3537 mL | 0.7075 mL | 1.7687 mL | |
| 50 mM | 0.0566 mL | 0.2830 mL | 0.5660 mL | 1.4149 mL | |
| 60 mM | 0.0472 mL | 0.2358 mL | 0.4716 mL | 1.1791 mL | |
| 80 mM | 0.0354 mL | 0.1769 mL | 0.3537 mL | 0.8843 mL | |
| 100 mM | 0.0283 mL | 0.1415 mL | 0.2830 mL | 0.7075 mL |