Orotidine
Based on 1 publication(s) in Google Scholar
Orotidine, a nucleotide, is an intermediate in pyrimidine nucleotide biosynthesis in RNA and DNA. Orotidine is mainly found in bacteria, fungi and plants.
For research use only. We do not sell to patients.
- Purity: 99.6%
- CAS No.: 314-50-1
- Formula: C10H12N2O8
- Molecular Weight:288.21
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Orotidine
MoreAll Endogenous Metabolite Isoforms
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Biological Activity
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Human Endogenous Metabolite |
Extant de novo biosynthetic pathway uses Orotidine 50-monophosphate to synthesize the canonical pyrimidine nucleotides in RNA and DNA. In this context, Orotidine is the only nucleotide that is synthesized through a ‘direct intermolecular nucleosidation’ step, with an attack of the fully-preformed nucleobase (orotic acid) on the activated 5-phosphoribosyl-diphosphate as opposed to the purine nucleotides whose heterocyclic rings are constructed stepwise on the sugar[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 314-50-1
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Appearance Solid
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Molecular Weight 288.21
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Formula C10H12N2O8
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Color White to yellow
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SMILES
OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(NC(C=C2C(O)=O)=O)=O)O1
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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J Adv Res
Antimycin A inhibits alpha-herpesvirus replication by disrupting the formation of pyrimidinosomes. [Abstract]2025 May 10:S2090-1232(25)00309-1. PMID: 40354935
Solvent & Solubility
H2O : 50 mg/mL (173.48 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (277 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 3.4697 mL | 17.3485 mL | 34.6969 mL | 86.7423 mL |
| 5 mM | 0.6939 mL | 3.4697 mL | 6.9394 mL | 17.3485 mL | |
| 10 mM | 0.3470 mL | 1.7348 mL | 3.4697 mL | 8.6742 mL | |
| 15 mM | 0.2313 mL | 1.1566 mL | 2.3131 mL | 5.7828 mL | |
| 20 mM | 0.1735 mL | 0.8674 mL | 1.7348 mL | 4.3371 mL | |
| 25 mM | 0.1388 mL | 0.6939 mL | 1.3879 mL | 3.4697 mL | |
| 30 mM | 0.1157 mL | 0.5783 mL | 1.1566 mL | 2.8914 mL | |
| 40 mM | 0.0867 mL | 0.4337 mL | 0.8674 mL | 2.1686 mL | |
| 50 mM | 0.0694 mL | 0.3470 mL | 0.6939 mL | 1.7348 mL | |
| 60 mM | 0.0578 mL | 0.2891 mL | 0.5783 mL | 1.4457 mL | |
| 80 mM | 0.0434 mL | 0.2169 mL | 0.4337 mL | 1.0843 mL | |
| 100 mM | 0.0347 mL | 0.1735 mL | 0.3470 mL | 0.8674 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Orotidine Related Classifications
HY-113226 Related Classifications
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