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Cat. No.: HY-173022

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BDM_92499

BDM_92499 is a nanomolar selective IRAP inhibitor, with an IC₅₀ of 3.4 nM. BDM_92499 also inhibits ERAP1 and ERAP2, with IC₅₀ values of 0.46 μM and 4.2 μM, respectively.

For research use only. We do not sell to patients.

Formula: C₂₅H₃₀N₄O₅
Molecular Weight:466.53

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

BDM_92499 Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

BDM_92499 is a nanomolar selective IRAP inhibitor, with an IC₅₀ of 3.4 nM. BDM_92499 also inhibits ERAP1 and ERAP2, with IC₅₀ values of 0.46 μM and 4.2 μM, respectively^[1].

All Aminopeptidase Isoforms :

CD13
LTA4H

Chemical Information

Molecular Weight 466.53
Formula C₂₅H₃₀N₄O₅
SMILES

NC([C@@H](NC(C(CC(C)C)C(NO)=O)=O)CC1=CNC2=CC=C(OCC3=CC=CC=C3)C=C21)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Ben He, et al. Discovery of New Nanomolar Selective IRAP Inhibitors. J Med Chem. 2025 Feb 27;68(4):4168-4195. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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BDM_92499

All Aminopeptidase Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

BDM_92499 Related Classifications

HY-173022 Related Classifications