BRI-12349
BRI-12349 (Compound 50) is a dual antagonist of CysLT1R/CysLT2R with Ki values of 1.03 and 6.46 μM. BRI-12349 can inhibit the generation of IP1 induced by LTD4 (the main ligand of CysLTs). BRI-12349 can be used for the research of immunology and inflammation, such as asthma.
For research use only. We do not sell to patients.
- CAS No.: 920707-33-1
- Formula: C17H13N5O3S2
- Molecular Weight:399.45
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Leukotriene Receptor Isoforms
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Biological Activity
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CysLT1 |
CysLT2 |
Chemical Information
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CAS No. 920707-33-1
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Molecular Weight 399.45
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Formula C17H13N5O3S2
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SMILES
O=C(C1=C(NC(CSC2=NN=C(C3=CNC4=C3C=CC=C4)O2)=O)SC=C1)N
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BRI-12349 Related Classifications
HY-176920 Related Classifications
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