country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-N19749

Copy Link Print Information

Decumbensine

(Synonyms: (+)-Decumbensine; (+)-Egenine)

Decumbensine ((+)-Egenine) is a phthalideisoquinoline hemiacetal alkaloid present in Corydalis decumbens. Decumbensine significantly inhibits spontaneous calcium oscillations in primary cultured neocortical neurons, reducing oscillation frequency and amplitude. Decumbensine can be used in studies related to central nervous system diseases, epilepsy and pain.

For research use only. We do not sell to patients.

CAS No.: 6883-44-9
Formula: C₂₀H₁₉NO₆
Molecular Weight:369.37

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Decumbensine Chemical Structure

CAS No.: 6883-44-9

Size

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Decumbensine ((+)-Egenine) is a phthalideisoquinoline hemiacetal alkaloid present in Corydalis decumbens^[1]^[2]^[3]. Decumbensine significantly inhibits spontaneous calcium oscillations in primary cultured neocortical neurons, reducing oscillation frequency and amplitude^[2]. Decumbensine can be used in studies related to central nervous system diseases, epilepsy and pain^[1]^[2].

All Calcium Channel Isoforms :

In Vitro

Decumbensine (6.8 μM) potently inhibits spontaneous calcium oscillations in primary cultured neocortical neurons with an IC₅₀ of 6.8 μM^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 6883-44-9
Molecular Weight 369.37
Formula C₂₀H₁₉NO₆
SMILES

CN1[C@](C2=C(CC1)C=C3C(OCO3)=C2)([H])[C@@]4([H])C5=C(C6=C(OCO6)C=C5)[C@H](O4)O
Synonyms

(+)-Decumbensine; (+)-Egenine
Structure Classification
- Alkaloids
- Isoquinoline Alkaloids
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Zhang JS,et al. Decumbensine and epi-α-Decumbensine: Two New Alkaloids Isolated from Corydalis decumbens. J Nat Prod. 1988 Nov-Dec;51(6):1241-1242.

[2]. Zhang CL,et al. Phthalideisoquinoline Hemiacetal Alkaloids from Corydalis decumbens That Inhibit Spontaneous Calcium Oscillations, Including Alkyl Derivatives of (+)-Egenine That Are Strikingly Levorotatory. J Nat Prod. 2019 Oct 25;82(10):2713-2720. [Content Brief]

[3]. Chang J,et al. Two novel isoquinoline alkaloids from the seedling of Corydalis decumbens. Tetrahedron Lett. 2015 Jan 1;56(1):225-228. doi: 10.1016/j.tetlet.2014.11.066.

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

Get Quote In-stock

Other size

Get Quote

Amount: USD 0.00

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

Product Name:
CAS No.:
Species:
Purity:
Quantity:

Decumbensine

All Calcium Channel Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Decumbensine Related Classifications

HY-N19749 Related Classifications