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Cat. No.: HY-N9928

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Echinenone

Echinenone is an acetylcholinesterase (AChE) inhibitor (IC₅₀=16.29 μg/mL) with anti-Aβ(25-35) activity. Echinenone can inhibit MDA content and increase superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GSH-Px) activities to cope with oxidative stress damage.

For research use only. We do not sell to patients.

CAS No.: 432-68-8
Formula: C₄₀H₅₄O
Molecular Weight:550.86

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (261 KB)

Echinenone Chemical Structure

CAS No.: 432-68-8

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

IC₅₀ & Target

AChE^[1]

All Cholinesterase (ChE) Isoforms :

AChE
BChE

Chemical Information

CAS No. 432-68-8
Molecular Weight 550.86
Formula C₄₀H₅₄O
SMILES

CC1(C)C(/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C(C(C)(CC2)C)=C(C)C2=O)=C(C)CCC1
Structure Classification
- Ketones, Aldehydes, Acids
Initial Source
- Animals
sea urchin
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (261 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Zhang T, et al. Understanding the mechanism of action of echinenone on Alzheimer's disease from the perspective of acetylcholinesterase and oxidative stress[J]. 2022.

Calculators

Molarity Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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Echinenone

All Cholinesterase (ChE) Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Echinenone Related Classifications

HY-N9928 Related Classifications