Florasulam
Based on 1 Customer Validation
Florasulam is a targeted post-emergent herbicide belonging to the triazolopyrimidine sulfonanilide class, which functions by inhibiting acetolactate synthase (ALS) in plants. Located in the chloroplasts, ALS plays a crucial role in the biosynthesis of branched-chain amino acids. When Florasulam inhibits ALS, it disrupts plant cell division, reduces growth, and ultimately leads to plant death.
For research use only. We do not sell to patients.
- Purity: 99.42%
- CAS No.: 145701-23-1
- Formula: C12H8F3N5O3S
- Molecular Weight:359.28
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
Biological Activity
Chemical Information
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CAS No. 145701-23-1
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Appearance Solid
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Molecular Weight 359.28
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Formula C12H8F3N5O3S
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Color White to off-white
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SMILES
O=S(NC1=C(F)C=CC=C1F)(C2=NN3C(OC)=NC=C(F)C3=N2)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
DMSO : 50 mg/mL (139.17 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (246 KB)
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SDS (458 KB)
- English - EN (458 KB)
- Français - FR (458 KB)
- Deutsch - DE (458 KB)
- Norwegian - NO (458 KB)
- Español - ES (458 KB)
- Swedish - SV (458 KB)
- Italian - IT (458 KB)
- Korean - KR (458 KB)
- Portuguese - PT (458 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.7833 mL | 13.9167 mL | 27.8334 mL | 69.5836 mL |
| 5 mM | 0.5567 mL | 2.7833 mL | 5.5667 mL | 13.9167 mL | |
| 10 mM | 0.2783 mL | 1.3917 mL | 2.7833 mL | 6.9584 mL | |
| 15 mM | 0.1856 mL | 0.9278 mL | 1.8556 mL | 4.6389 mL | |
| 20 mM | 0.1392 mL | 0.6958 mL | 1.3917 mL | 3.4792 mL | |
| 25 mM | 0.1113 mL | 0.5567 mL | 1.1133 mL | 2.7833 mL | |
| 30 mM | 0.0928 mL | 0.4639 mL | 0.9278 mL | 2.3195 mL | |
| 40 mM | 0.0696 mL | 0.3479 mL | 0.6958 mL | 1.7396 mL | |
| 50 mM | 0.0557 mL | 0.2783 mL | 0.5567 mL | 1.3917 mL | |
| 60 mM | 0.0464 mL | 0.2319 mL | 0.4639 mL | 1.1597 mL | |
| 80 mM | 0.0348 mL | 0.1740 mL | 0.3479 mL | 0.8698 mL | |
| 100 mM | 0.0278 mL | 0.1392 mL | 0.2783 mL | 0.6958 mL |