Forphenicine
Forphenicine is a bacterial metabolite that is found in S. fulvoviridis and an inhibitor of alkaline phosphatase. Forphenicine inhibits the growth of HL-60 leukemia cells at 10 µM. Forphenicine also increases survival in a guinea pig model of experimental autoimmune encephalomyelitis (EAE).
For research use only. We do not sell to patients.
- CAS No.: 57784-96-0
- Formula: C9H9NO4
- Molecular Weight:195.17
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
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Pentacosafluorotridecanoic Acid (Standard)
Biological Activity
Description
Chemical Information
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CAS No. 57784-96-0
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Molecular Weight 195.17
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Formula C9H9NO4
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SMILES
OC([C@H](C1=CC(O)=C(C=C1)C=O)N)=O
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Structure Classification
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Initial Source
Actinomyces fulvoviridis var
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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How to Select a Suitable Non-Mouse Animal Model
Selecting a suitable non-mouse animal model is a structured decision based on the research question, required anatomy or physiology, disease mechanism, endpoint feasibility, translational relevance, and ethical justification. Non-mouse models are preferred when mice cannot reproduce key human-relevant features, such as organ size, surgical anatomy, cardiovascular physiology, neuroanatomy, immune features, pharmacology, toxicology, or long-term clinical procedures. Candidate species may include rats, rabbits, guinea pigs, ferrets, zebrafish, pigs, sheep, goats, dogs, cats, horses, and non-human primates, but each species must be justified by its specific scientific advantage rather than convenience or tradition. Unresolved questions include how to quantify translational superiority across species, how to balance increased biological relevance against higher ethical burden, and when human-derived systems or new approach methodologies should replace animal use.
Purity & Documentation
References
[1]. Miura K, et al. Effects of enzyme inhibitors in inhibiting the growth and inducing the differentiation of human promyelocytic leukemia cells, HL-60. J Antibiot (Tokyo). 1986 May;39(5):734-5. [Content Brief]
[2]. Aoyagi T, et al. Forphenicine, and inhibitor of alkaline phosphatase produced by actinomycetes. J Antibiot (Tokyo). 1978 Mar;31(3):244-6. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Forphenicine Related Classifications
HY-N12108 Related Classifications
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