VD4162
VD4162 (Compound 8b) is a macrocyclic inhibitor of serine proteases. VD4162 can significantly improve potency for all four target enzymes TMPRSS2 (IC50 = 3.7 nM), HGFA(IC50 = 3.3 nM), matriptase (IC50 = 2.9 nM), and hepsin (IC50 = 0.54 nM). VD4162 can be used for the research of cancer.
For research use only. We do not sell to patients.
- CAS No.: 2574390-19-3
- Formula: C41H47N9O6S
- Molecular Weight:793.93
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Chemical Information
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CAS No. 2574390-19-3
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Molecular Weight 793.93
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Formula C41H47N9O6S
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SMILES
O=C1[C@@H](CC2=CNC3=C2C=CC=C3)NC([C@H](CC4=CC=C(OCCCC[C@@H](C(N[C@H](C(C5=NC6=C(C=CC=C6)S5)=O)CCCNC(N)=N)=O)N1)C=C4)NC(C)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
VD4162 Related Classifications
HY-161370 Related Classifications
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