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VEGFR-2-IN-52

VEGFR-2-IN-52 (compound 14d) is a potent VEGFR-2 inhibitor with an IC50 value of 191.1 nM. VEGFR-2-IN-52 decreases the protein expression of p-VEGFR-2, MMP9, p-ERK1/2 and p-MEK1. VEGFR-2-IN-52 shows cytotoxicity. VEGFR-2-IN-52 induces apoptosis and cell cycle arrest at G0/G1 phase. VEGFR-2-IN-52 increases the levels of ROS.

For research use only. We do not sell to patients.

  • CAS No.: 3046428-94-5
  • Formula: C20H25ClN4O2S
  • Molecular Weight:420.96
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • VEGFR-2-IN-52 Chemical Structure
    VEGFR-2-IN-52 Chemical Structure
CAS No.: 3046428-94-5
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All VEGFR Isoforms

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  • VEGFR-2-IN-52 Chemical Structure
    VEGFR-2-IN-52 Chemical Structure
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  • VEGFR-2-IN-52