VEGFR-2-IN-53
VEGFR-2-IN-53 (Compound 15w) is a VEGFR-2 inhibitor with an IC50 of 4.34 μM. VEGFR-2-IN-53 induces apoptosis by inhibiting VEGFR-2 activity and preventing cell migration, thereby exhibiting anti-angiogenic effects. The IC50 value of VEGFR-2-IN-53 for inhibiting MCF-7 cell growth is 3.87 μM. VEGFR-2-IN-53 can be used in cancer research.
For research use only. We do not sell to patients.
- Formula: C29H23N5O2S
- Molecular Weight:505.59
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All VEGFR Isoforms
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Biological Activity
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VEGFR2 4.34 μM (IC50) |
Chemical Information
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Molecular Weight 505.59
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Formula C29H23N5O2S
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SMILES
O=C(NC1=NC2=C(C=CC=C2)S1)[C@H]3[C@H](C4=C(C)N(C5=CC=CC=C5)N=C4C)[C@@](C6=CC=CC=C6N7)3C7=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)