VEGFR-2-IN-79
VEGFR-2-IN-79 (Compound 17) is a VEGFR-2 inhibitor with an IC50 of 2.32 μM. VEGFR-2-IN-79 exhibits potent and broad-spectrum cytotoxicity and can induce apoptosis in MCF-7 cells. VEGFR-2-IN-79 does not cause a significant decrease in the mitochondrial membrane potential of MCF-7 cells. VEGFR-2-IN-79 can be used for research on breast cancer.
For research use only. We do not sell to patients.
- Formula: C26H21ClF6N4O3S2
- Molecular Weight:651.04
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All VEGFR Isoforms
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Biological Activity
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VEGFR2 2.32 μM (IC50) |
Chemical Information
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Molecular Weight 651.04
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Formula C26H21ClF6N4O3S2
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SMILES
CC1=C(C=C(C(S(=O)(NC(NNC(/C=C/C2=CC=C(C=C2)C(F)(F)F)=O)=N)=O)=C1)SCC3=CC=C(C=C3)C(F)(F)F)Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)