VGN50
VGN50 is a bioactive molecule that mimics the function of K-Rta and down-regulates MYC-mediated gene transcription. VGN50 has antitumor activity.
For research use only. We do not sell to patients.
- Formula: C121H218N46O32
- Molecular Weight:2829.31
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
VGN50 (24 μM, 24 h) Down-regulates the expression of MYC in BCBL-1 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:PEL xenograft mouse model[1]
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Dosage:10 mg/kg
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Administration:i.p., for 10 consecutive days
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Result:Ascites containing tumors accumulate without weight gain.
Chemical Information
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Molecular Weight 2829.31
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Formula C121H218N46O32
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Sequence
{d-Arg}-Lys-Lys-Arg-Arg-{Orn}-Arg-Arg-Arg-{βAla}-Leu-Ser-Ser-Ile-Leu-Gln-Gly-Leu-Tyr-Gln-Leu-Asp-Thr
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Sequence Shortening
{d-Arg}-KKRR-{Orn}-RRR-{βAla}-LSSILQGLYQLDT
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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