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WJ460 

Cat. No.: HY-124632
Handling Instructions

WJ460 is a potent myoferlin (MYOF) inhibitor, which interacts directly with MYOF and exerts anti-metastatic activity in the nanomolar range in breast cancer cells.

For research use only. We do not sell to patients.

WJ460 Chemical Structure

WJ460 Chemical Structure

CAS No. : 1415251-36-3

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Description

WJ460 is a potent myoferlin (MYOF) inhibitor, which interacts directly with MYOF and exerts anti-metastatic activity in the nanomolar range in breast cancer cells[1].

IC50 & Target

MYOF[1]

In Vitro

WJ460 blocks breast cancer cell invasion with IC50 values of 43.37 ± 3.42 nM in MDA-MB-231 and 36.40 ± 4.51 nM in BT549 cells. WJ460 treatment remarkably inhibits MDA-MB-231 and BT549 cell invasion through Collagen I in a dose-dependent manner[1].

In Vivo

WJ460 inhibits breast tumor growth, angiogenesis, and spontaneous metastasis in a spontaneous metastasis model[1].

Molecular Weight

460.59

Formula

C₂₇H₂₈N₂O₃S

CAS No.

1415251-36-3

SMILES

O=C(NCCCCC1=CC=CC=C1)C2=CC=CC(C(N3C4=CC=CC=C4OC)SCC3=O)=C2

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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WJ460
Cat. No.:
HY-124632
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