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Cat. No.: HY-D3640

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WX-02-13

WX-02-13 is an inactive enantiomer of WX-02-33 (HY-D3639). WX-02-33 is a TOE1 inhibitor. WX-02-13 can be used in research on Merkel cell carcinoma.

For research use only. We do not sell to patients.

CAS No.: 3020765-75-4
Formula: C₂₆H₂₅N₃O₅
Molecular Weight:459.49

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (292 KB)

WX-02-13 Chemical Structure

CAS No.: 3020765-75-4

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

WX-02-13 is an inactive enantiomer of WX-02-33 (HY-D3639). WX-02-33 is a TOE1 inhibitor. WX-02-13 can be used in research on Merkel cell carcinoma^[1].

In Vitro

WX-02-13 (20 µM; 6 h) produces much weaker inhibition of WT-TOE1 deadenylation in MCC142 cells than WX-02-33^[1].
WX-02-13 (20 µM; 6 h) does not promote the TOE1-spliceosome interaction in MCC142 cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 3020765-75-4
Molecular Weight 459.49
Formula C₂₆H₂₅N₃O₅
SMILES

C=CC(N1[C@@H](C2=CC=C(OCO3)C3=C2)C4=C(C[C@H]1C(N5CCOCC5)=O)C6=CC=CC=C6N4)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (292 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Li H, et al. Assigning functionality to cysteines by base editing of cancer dependency genes. Nature chemical biology. 2023 Nov;19(11):1320-1330.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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