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Cat. No.: HY-15070

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YM 900

YM 900 is an AMPA receptor antagonist.

For research use only. We do not sell to patients.

CAS No.: 143151-35-3
Formula: C₁₁H₇N₅O₄
Molecular Weight:273.20

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

YM 900 Chemical Structure

CAS No.: 143151-35-3

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

YM 900 is an AMPA receptor antagonist^[1].

All iGluR Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
Oocyte	IC₅₀	0.3 μM Compound: YM-90K	Antagonistic activity against rat ionotropic glutamate receptor ionotropic kainate in xenopus oocytes Antagonistic activity against rat ionotropic glutamate receptor ionotropic kainate in xenopus oocytes	[PMID: 8568808]
Oocyte	IC₅₀	260 nM Compound: YM90K	Antagonistic activity against Ionotropic glutamate receptor AMPA using kainate-evoked current in Xenopus oocytes injected with rat brain mRNA Antagonistic activity against Ionotropic glutamate receptor AMPA using kainate-evoked current in Xenopus oocytes injected with rat brain mRNA	[PMID: 11133083]
Oocyte	IC₅₀	260 nM Compound: YM-90K	Inhibitory activity against generation of currents by 50 uM kainate in Xenopus oocytes injected with rat brain mRNA Inhibitory activity against generation of currents by 50 uM kainate in Xenopus oocytes injected with rat brain mRNA	[PMID: 10843235]
Oocyte	IC₅₀	30.5 μM Compound: YM-90K	Antagonistic activity against N-methyl-D-aspartate glutamate receptor 1 in Xenopus oocytes Antagonistic activity against N-methyl-D-aspartate glutamate receptor 1 in Xenopus oocytes	[PMID: 8568808]

Chemical Information

CAS No. 143151-35-3
Molecular Weight 273.20
Formula C₁₁H₇N₅O₄
SMILES

O=C(N1)C(NC(C1=C2)=CC([N+]([O-])=O)=C2N3C=CN=C3)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Petitet F, et al. Effects of AMPA receptor modulators on the production of arachidonic acid from striatal neurons. Eur J Pharmacol. 1995 Oct 15;291(2):143-51. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

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100 mg

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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YM 900

All iGluR Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

YM 900 Related Classifications

HY-15070 Related Classifications