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Cat. No.: HY-134125

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Yohimbic acid ethyl ester

Yohimbic acid ethyl ester (Compound 3a) is a selective ADRA2A antagonist with an IC₅₀ of 31 nM.

For research use only. We do not sell to patients.

CAS No.: 73840-32-1
Formula: C₂₂H₂₈N₂O₃
Molecular Weight:368.47

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Yohimbic acid ethyl ester Chemical Structure

CAS No.: 73840-32-1

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Yohimbic acid ethyl ester (Compound 3a) is a selective ADRA2A antagonist with an IC₅₀ of 31 nM^[1].

All Adrenergic Receptor Isoforms :

Chemical Information

CAS No. 73840-32-1
Molecular Weight 368.47
Formula C₂₂H₂₈N₂O₃
SMILES

O=C([C@@H]1[C@@]2([H])C[C@@]3([H])C4=C(CCN3C[C@]2([H])CC[C@@H]1O)C5=CC=CC=C5N4)OCC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Chayka A, et al. Structure-Based Drug Design of ADRA2A Antagonists Derived from Yohimbine. J Med Chem. 2024 Jun 27;67(12):10135-10151. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Chemical Information
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Yohimbic acid ethyl ester

All Adrenergic Receptor Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Yohimbic acid ethyl ester Related Classifications

HY-134125 Related Classifications