Zintevir
Zintevir is an antisense oligonucleotide that targets HIV-1 integrase.
For research use only. We do not sell to patients.
- CAS No.: 171345-51-0
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
-
CAS No. 171345-51-0
-
SMILES
[Zintevir]
-
Synonyms
AR177; T30177
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Ojwang JO, Buckheit RW, Pommier Y, et al. T30177, an oligonucleotide stabilized by an intramolecular guanosine octet, is a potent inhibitor of laboratory strains and clinical isolates of human immunodeficiency virus type 1. Antimicrob Agents Chemother. 1995;39(11):2426-2435. [Content Brief]
[2]. Mukundan VT, Do NQ, Phan AT. HIV-1 integrase inhibitor T30177 forms a stacked dimeric G-quadruplex structure containing bulges. Nucleic Acids Res. 2011;39(20):8984-8991. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)