1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. γ-Glutamylornithine

γ-Glutamylornithine is the urine excreta of patients with HHH syndrome (hyperuricemia, hyperaminemia, and hypercitrullinuria) and rotary atrophy associated with hyperuricemia. Increased levels of endogenous ornithine increase levels of γ-Glutamylornithine in the urine.

For research use only. We do not sell to patients.

γ-Glutamylornithine Chemical Structure

γ-Glutamylornithine Chemical Structure

CAS No. : 56523-61-6

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5 mg USD 380 In-stock
10 mg USD 600 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

γ-Glutamylornithine is the urine excreta of patients with HHH syndrome (hyperuricemia, hyperaminemia, and hypercitrullinuria) and rotary atrophy associated with hyperuricemia. Increased levels of endogenous ornithine increase levels of γ-Glutamylornithine in the urine[1].

IC50 & Target

Human Endogenous Metabolite

 

Molecular Weight

261.27

Formula

C10H19N3O5

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC([C@H](CCCN)NC(CC[C@H](N)C(O)=O)=O)=O

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

H2O : 125 mg/mL (478.43 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.8275 mL 19.1373 mL 38.2746 mL
5 mM 0.7655 mL 3.8275 mL 7.6549 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Dilution Calculator

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 3.8275 mL 19.1373 mL 38.2746 mL 95.6865 mL
5 mM 0.7655 mL 3.8275 mL 7.6549 mL 19.1373 mL
10 mM 0.3827 mL 1.9137 mL 3.8275 mL 9.5686 mL
15 mM 0.2552 mL 1.2758 mL 2.5516 mL 6.3791 mL
20 mM 0.1914 mL 0.9569 mL 1.9137 mL 4.7843 mL
25 mM 0.1531 mL 0.7655 mL 1.5310 mL 3.8275 mL
30 mM 0.1276 mL 0.6379 mL 1.2758 mL 3.1895 mL
40 mM 0.0957 mL 0.4784 mL 0.9569 mL 2.3922 mL
50 mM 0.0765 mL 0.3827 mL 0.7655 mL 1.9137 mL
60 mM 0.0638 mL 0.3190 mL 0.6379 mL 1.5948 mL
80 mM 0.0478 mL 0.2392 mL 0.4784 mL 1.1961 mL
100 mM 0.0383 mL 0.1914 mL 0.3827 mL 0.9569 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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γ-Glutamylornithine Related Classifications

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γ-Glutamylornithine
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