2,6-Dimethylnaphthalene
Based on 1 Customer Validation
2,6-Dimethylnaphthalene is a cytochrome P450 1A2 (CYP1A2) inhibitor, with an IC50 of 52 μM and a pIC50 of 4.28 against human targets. 2,6-Dimethylnaphthalene inhibits the 7-ethoxyresorufin O-dealkylation activity catalyzed by CYP1A2.
For research use only. We do not sell to patients.
- Purity: 99.88%
- CAS No.: 581-42-0
- Formula: C12H12
- Molecular Weight:156.22
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Description
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CYP1A2 52 μM (IC50) |
CYP1A2 4.28 μM (pIC50) |
In Vitro
2,6-Dimethylnaphthalene (10 min preincubation; 20 min incubation) inhibits recombinant human CYP1A2-mediated 7-ethoxyresorufin O-dealkylation with an IC50 of 52 µM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 581-42-0
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Appearance Solid
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Molecular Weight 156.22
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Formula C12H12
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Color White to off-white
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SMILES
CC1=CC(C=CC(C)=C2)=C2C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (271 KB)
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SDS (458 KB)
- English - EN (458 KB)
- Français - FR (458 KB)
- Deutsch - DE (458 KB)
- Norwegian - NO (458 KB)
- Español - ES (458 KB)
- Swedish - SV (458 KB)
- Italian - IT (458 KB)
- Korean - KR (458 KB)
- Portuguese - PT (458 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)