1. Natural Products
  2. Plants Terpenoids
  3. Celastraceae Diterpenoids
  4. Tripterygium wilfordii Hook. f.
  5. 2-Epitripdiolide

2-Epitripdiolide is a diterpenoid compound derived from Tripterygium hypoglaucum with significant antitumor activity. Its IC50 values against A549, KB, KBvin, and MDA-MB-231 cells are 1.34, 0.4, 4.4, and 1.2 nM, respectively.

For research use only. We do not sell to patients.

2-Epitripdiolide Chemical Structure

2-Epitripdiolide Chemical Structure

CAS No. : 74409-90-8

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Description

2-Epitripdiolide is a diterpenoid compound derived from Tripterygium hypoglaucum with significant antitumor activity. Its IC50 values against A549, KB, KBvin, and MDA-MB-231 cells are 1.34, 0.4, 4.4, and 1.2 nM, respectively[1].

Molecular Weight

376.40

Formula

C20H24O7

CAS No.
SMILES

C[C@@]12[C@@]34[C@]5([C@@H]([C@@]6([C@](O6)([H])[C@]3([H])O4)C(C)C)O)[C@@](C[C@@]1([H])C7=C(C(OC7)=O)[C@@H](C2)O)([H])O5

Structure Classification
Initial Source
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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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2-Epitripdiolide
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