2-Heptanol
Based on 1 Customer Validation
2-Heptanol is one of the chemical compounds identified in turmeric and turmeric rhizome essential oil. 2-Heptanol can speed up amino acid metabolism and slow down membrane transport, exhibiting antibacterial activity. The rhizome essential oil has good antibacterial and antioxidant properties.
For research use only. We do not sell to patients.
- Purity: 99.65%
- CAS No.: 543-49-7
- Formula: C7H16O
- Molecular Weight:116.20
-
Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
Biological Activity
2-Heptanol (0-20 μL cm-3, 5 days) inhibits the mycelial growth of B. cinereal in vitro in a dose-dependent manner[1].
2-Heptanol (0-0.16 mL cm-3, placed on a perforated partition, 4 days) shows significant antifungal effects in tomatoes[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Cell Line:B. cinereal
-
Concentration:0, 0.05, 0.1, 0.16, 0.21 μL cm-3
-
Incubation Time:5 days
-
Result:Inhibited the growth of mycelium in a dose-dependent manner, the inhibition rate of 0.05 μL cm-3 on mycelium growth is 18.35%.
-
Animal Model:Inoculation of tomato with B. cinerea mycelium plug[1]
-
Dosage:0, 0.05, 0.1, 0.16, 0.21 μL cm-3, 4 days
-
Administration:Placed on a perforated partition
-
Result:Reduced the diameter of the lesion, increased the activity of catalase (CAT), and increased the activity of peroxidase (POD).
Chemical Information
-
CAS No. 543-49-7
-
Appearance Liquid (Density: 0.817 g/cm3)
-
Molecular Weight 116.20
-
Formula C7H16O
-
Color Colorless to light yellow
-
SMILES
CC(O)CCCCC
-
Structure Classification
-
Initial Source
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
DMSO : 100 mg/mL (860.59 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (21.51 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (21.51 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Please enter the basic information of animal experiments:
-
-
-
-
Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
-
%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
-
%+
-
+%Tween-80 + +
-
%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
-
Data Sheet (269 KB)
-
SDS (604 KB)
- English - EN (604 KB)
- Français - FR (604 KB)
- Deutsch - DE (604 KB)
- Norwegian - NO (604 KB)
- Español - ES (604 KB)
- Swedish - SV (604 KB)
- Italian - IT (604 KB)
- Korean - KR (604 KB)
- Portuguese - PT (604 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 8.6059 mL | 43.0293 mL | 86.0585 mL | 215.1463 mL |
| 5 mM | 1.7212 mL | 8.6059 mL | 17.2117 mL | 43.0293 mL | |
| 10 mM | 0.8606 mL | 4.3029 mL | 8.6059 mL | 21.5146 mL | |
| 15 mM | 0.5737 mL | 2.8686 mL | 5.7372 mL | 14.3431 mL | |
| 20 mM | 0.4303 mL | 2.1515 mL | 4.3029 mL | 10.7573 mL | |
| 25 mM | 0.3442 mL | 1.7212 mL | 3.4423 mL | 8.6059 mL | |
| 30 mM | 0.2869 mL | 1.4343 mL | 2.8686 mL | 7.1715 mL | |
| 40 mM | 0.2151 mL | 1.0757 mL | 2.1515 mL | 5.3787 mL | |
| 50 mM | 0.1721 mL | 0.8606 mL | 1.7212 mL | 4.3029 mL | |
| 60 mM | 0.1434 mL | 0.7172 mL | 1.4343 mL | 3.5858 mL | |
| 80 mM | 0.1076 mL | 0.5379 mL | 1.0757 mL | 2.6893 mL | |
| 100 mM | 0.0861 mL | 0.4303 mL | 0.8606 mL | 2.1515 mL |