country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-132460S

Copy Link Print Information

2-Hydroxy nevirapine-d₃

2-Hydroxy nevirapine-d₃ (2-OH NVP-d₃) is the deuterated-labeled 2-Hydroxy nevirapine (2-OH NVP) (HY-W739986). 2-Hydroxy nevirapine (2-OH NVP) is a phase I metabolite of Nevirapine (HY-10570) and an Aryl Hydrocarbon Receptor activator. It induces hepatic Apolipoprotein A1 levels and modulates paraoxonase-1 enzyme activity. 2-Hydroxy nevirapine is used in research on atherosclerosis and HIV-1 infection.

For research use only. We do not sell to patients.

CAS No.: 1329834-05-0
Formula: C₁₅H₁₁D₃N₄O₂
Molecular Weight:285.32

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (277 KB)

2-Hydroxy nevirapine-d₃ Chemical Structure

CAS No.: 1329834-05-0

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Application
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

CAS No. 1329834-05-0
Unlabeled CAS 254889-31-1
Molecular Weight 285.32
Formula C₁₅H₁₁D₃N₄O₂
SMILES

[2H]C([2H])(C1=CC(O)=NC2=C1NC(C3=CC=CN=C3N2C4CC4)=O)[2H]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (277 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Marinho AT, et al. The 2-hydroxy-nevirapine metabolite as a candidate for boosting apolipoprotein A1 and for modulating anti-HDL antibodies. Pharmacological research. 2021 Mar;165:105446.

[2]. Aline T, et al. Development and validation of an HPLC-UV method for quantifying nevirapine and its main phase I metabolites in human blood. Anal. Methods 2014; 6 (5): 1575-1580.

[3]. Pinheiro PF, et al. Sex differences in hepatic and intestinal contributions to nevirapine biotransformation in rats. Chemico-biological interactions. 2015 May 25;233:115-21.

[4]. Marinho AT, et al. Nevirapine modulation of paraoxonase-1 in the liver: An in vitro three-model approach. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2016 Jan 20;82:147-53.

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

Get Quote In-stock

Other size

Get Quote

Amount: USD 0.00

Biological Activity
- Description
- Application
Chemical Information
Purity & Documentation
References

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

Product Name:
CAS No.:
Species:
Purity:
Quantity:

2-Hydroxy nevirapine-d3

Biological Activity

Description

Application

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

2-Hydroxy nevirapine-d3 Related Classifications

HY-132460S Related Classifications

Bioz

Keywords

Your Recently Viewed Products

2-Hydroxy nevirapine-d₃

2-Hydroxy nevirapine-d₃ Related Classifications