(3S,5S)-Atorvastatin sodium salt
(3S,5S)-Atorvastatin sodium salt is a pregnane X receptor (PXR) activator and the inactive enantiomer of Atorvastatin. Atorvastatin is an orally active HMG-CoA reductase inhibitor with lipid-lowering capabilities.
For research use only. We do not sell to patients.
- CAS No.: 1428118-38-0
- Formula: C33H34FN2NaO5
- Molecular Weight:580.62
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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HY-17502
Simvastatin
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HY-17504A
Rosuvastatin
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HY-B0144A
Pitavastatin
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HY-17408
Mevastatin
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HY-B0165A
Pravastatin sodium
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HY-115292
Simvastatin hydroxy acid sodium
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HY-B0144
Pitavastatin Calcium
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HY-123672
Lovastatin hydroxy acid sodium
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HY-B0165AR
Pravastatin sodium (Standard)
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HY-17502R
Simvastatin (Standard)
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HY-17408R
Mevastatin (Standard)
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HY-17504B
Rosuvastatin Sodium
Biological Activity
Pregnane X receptor (PXR)[1].
Chemical Information
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CAS No. 1428118-38-0
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Molecular Weight 580.62
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Formula C33H34FN2NaO5
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SMILES
O=C(NC1=CC=CC=C1)C2=C(N(C(C3=CC=C(C=C3)F)=C2C4=CC=CC=C4)CC[C@@H](C[C@@H](CC(O[Na])=O)O)O)C(C)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Kocarek TA, et al. Regulation of CYP2B6 and CYP3A expression by hydroxymethylglutaryl coenzyme A inhibitors in primary cultured human hepatocytes. Drug Metab Dispos. 2002 Dec;30(12):1400-5. [Content Brief]
[2]. Korhonova M, et al. Optical Isomers of Atorvastatin, Rosuvastatin and Fluvastatin Enantiospecifically Activate Pregnane X Receptor PXR and Induce CYP2A6, CYP2B6 and CYP3A4 in Human Hepatocytes. PLoS One. 2015 Sep 14;10(9):e0137720. [Content Brief]
[3]. Shcherbakova EG, et al. High-Throughput Assay for Enantiomeric Excess Determination in 1,2- and 1,3-Diols and Direct Asymmetric Reaction Screening. Chemistry. 2017 Jul 26;23(42):10222-10229. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(3S,5S)-Atorvastatin sodium salt Related Classifications
HY-123632 Related Classifications
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