2. GPCR/G Protein Neuronal Signaling
  3. mAChR
  4. 4,4-Difluorobenzhydrol

4,4-Difluorobenzhydrol  (Synonyms: Bis(4-fluorophenyl)methanol)

Cat. No.: HY-W037331 Purity: 98.21%
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4,4-Difluorobenzhydrol is a precursor of a mAChR antagonist, and its derivative 4,4-Difluorobenzhydrol Carbamate can selectively target the M1 subtype.

For research use only. We do not sell to patients.

4,4-Difluorobenzhydrol

4,4-Difluorobenzhydrol Chemical Structure

CAS No. : 365-24-2

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
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Solid
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4,4-Difluorobenzhydrol Related Antibodies

Top Publications Citing Use of Products

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mAChR1 mAChR2 mAChR3 mAChR4 mAChR5

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Description

4,4-Difluorobenzhydrol is a precursor of a mAChR antagonist, and its derivative 4,4-Difluorobenzhydrol Carbamate can selectively target the M1 subtype[1].

Molecular Weight

220.21

Formula

C13H10F2O
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC(C1=CC=C(F)C=C1)C2=CC=C(F)C=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Store at room temperature 3 years

In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (454.11 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.5411 mL 22.7056 mL 45.4112 mL
5 mM 0.9082 mL 4.5411 mL 9.0822 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.5411 mL 22.7056 mL 45.4112 mL 113.5280 mL
5 mM 0.9082 mL 4.5411 mL 9.0822 mL 22.7056 mL
10 mM 0.4541 mL 2.2706 mL 4.5411 mL 11.3528 mL
15 mM 0.3027 mL 1.5137 mL 3.0274 mL 7.5685 mL
20 mM 0.2271 mL 1.1353 mL 2.2706 mL 5.6764 mL
25 mM 0.1816 mL 0.9082 mL 1.8164 mL 4.5411 mL
30 mM 0.1514 mL 0.7569 mL 1.5137 mL 3.7843 mL
40 mM 0.1135 mL 0.5676 mL 1.1353 mL 2.8382 mL
50 mM 0.0908 mL 0.4541 mL 0.9082 mL 2.2706 mL
60 mM 0.0757 mL 0.3784 mL 0.7569 mL 1.8921 mL
80 mM 0.0568 mL 0.2838 mL 0.5676 mL 1.4191 mL
100 mM 0.0454 mL 0.2271 mL 0.4541 mL 1.1353 mL
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4,4-Difluorobenzhydrol Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

4,4-Difluorobenzhydrol365-24-2Bis(4-fluorophenyl)methanolmAChRMuscarinic acetylcholine receptorInhibitorinhibitorinhibit

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